Results 71 to 80 of about 6,792,361 (251)

Early medieval war-flails (kistens) from Polish lands

open access: yesFasciculi Archaeologiae Historicae, 2008
...
Piotr N. Kotowicz
doaj  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

След края – ранновизантийско и средновековно присъствие в църква Extra Muros до крепостта Бузово кале, Казанлъшко

open access: yesПриноси към българската археология, 2018
The article presents the results of the archaeological excavations at an extra muros church, situated on the northern slope of the Sarnena Gora Mountain, not far from the village of Buzovgrad, Kazanlak region (Figs. 1–3). Built in the early 6th century,
Deyan Rabovyanov   +2 more
doaj  

La mission archéologique de Jebel Oust, site antique de Tunisie

open access: yesArchéopages, 2010
The Tunisian site of Jebel Oust (beginnings of the Empire to early 7th c.) is a place of worship (temple) associated with a hot spring (thermae and tanks).
Raphaël Durost   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Medieval Stained Glass: Text and Context

open access: yes, 2006
Lecture held April 4, 2006, 7 p.m. in Woodward Hall, UNM as the third lecture of the Institute for Medieval Studies' Spring Lecture Series 2006.The development of a method for creating stained glass windows was one of the outstanding technical ...
Raguin, Virginia Chieffo
core  

Introduction: The Middle Ages

open access: yes, 2020
Episcopal sees were established from the early Middle Ages on, at first in Denmark from the middle of the tenth century, and a little bit later in Norway and Sweden.
Bertil Nilsson   +4 more
core   +1 more source

The erotics of consolation: desire and distance in the late middle ages

open access: yes, 2008
A themed volume of essays on the varied ways in which medieval literature of the later Middle Ages engaged with discourses of love and loss, mourning and consolation from Classical and Christian traditions, notably Boethius.
Milner, Stephen, LEGLU, Catherine
core   +1 more source

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