Results 121 to 130 of about 1,361,869 (313)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Vertèbres d’un ange de mer

open access: yesArchéopages, 2023
Stéphane Augry
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Da usi civici a beni comuni : gli studi sulla proprietà collettiva nella medievistica e nella modernistica italiana e le principali tendenze internazionali [PDF]

open access: yes, 2016
This paper aims to gather and summarize the studies on collective properties and the commons developed by historians of the Middle Ages and Early Modern times in Italy during the last two centuries.
Cristoferi, Davide
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Conference Review: EXARC at the International Congress on Medieval Studies in Kalamazoo, Michigan (USA)

open access: yesEXARC Journal, 2017
The International Congress on Medieval Studies is held at Western Michigan University in Kalamazoo each May. Now in its 52nd year, ICMS draws around 3,000 people attending approximately 575 sessions of papers, panel discussions, round tables, workshops ...
Neil Peterson, Karen Davidson
doaj  

Open Learning Environment in Early Modern Low Countries History [PDF]

open access: yes, 2010
This project, part of the individual strand of JISC’s and the Higher Education Academy’s Open Educational Resources pilot programme, will turn a comprehensive survey course in Early Modern Low Countries history, from the late Middle Ages to the end of ...
Tiedau, U
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

An Agglomeration of Early Middle Ages: Meda'in

open access: yes, 2014
The group of the cities of Meda'in, the administrative capital of the Sassanid Empire from the early Middle Ages to the collapse of this empire, is one of the biggest metropolises of the antiquity and of the Middle Ages. The group of the cities of Meda'in, consisting of many cities and towns built in different sizes and various times, has a diverse ...
Bakir, Abdulhalik, Altungök, Ahmet
openaire   +2 more sources

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