Results 21 to 30 of about 253,053 (265)

¿Cómo pensamos la política de la edad moderna ? une reflexión historiográfica / personal

open access: yesL'Atelier du CRH, 2011
In our everyday life, we all refer to a certain common notion of politics: we know what a parliament, a political party, and ideology are, thoughsuch a general knowledge does not allow us to question the relations between theory and practice, for example.
Saúl Martínez Bermejo
doaj   +1 more source

Apports de l’archéologie à la connaissance des économies salicoles sur les côtes de la Manche (Protohistoire-époque moderne)

open access: yesArchéopages, 2019
Recent work has shown that salt-making was one of the most important and long-lasting activities carried out in coastal areas on both sides of the Channel since recent prehistory.
Vincent Carpentier, Cyril Marcigny
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Bawds, Midwifery, and the Evil Eye in Golden Age Spanish Literature and Medicine

open access: yesHumanities, 2023
This article explores the relationship between the alcahueta or bawd, the evil eye, and midwifery in the early modern Spanish cultural imaginary.
Emily Kuffner
doaj   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

GLOBALIZATION - EARLY PHENOMENON MODERN AGE

open access: yes, 2020
Recently, among the historians of the early modern period, a substantial attention is given for the term globalization, moreover the history of globalization and its development as a phenomenon. According to researchers of the early modern era (as well as researchers in other social science disciplines) the beginnings of globalization, in the form in ...
openaire   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Domesticating Colour in the Early Modern Age: Dyeing Wool in Black in Portugal

open access: yesHeritage
Mastering a colour—as such, its ‘domestication’—involves a weft of technological and symbolic relationships encompassed in the human ability to reproduce a visible colour using the techniques of textile dyeing.
Luís Gonçalves Ferreira
doaj   +1 more source

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