Results 31 to 40 of about 284,976 (311)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Výskum hradu Dobrá Niva v rokoch 2013 a 2014
Cieľom príspevku je predstaviť a interpretovať nálezovú situáciu na NKP Hrad Dobrá Niva v katastrálnom území obce Podzámčok, okres Zvolen. Archeologický výskum uskutočnený v rokoch 2013 a 2014 priniesol nové informácie o vrcholno- a neskorostredovekom až
Noémi Beljak Pažinová +2 more
doaj +1 more source
Bawds, Midwifery, and the Evil Eye in Golden Age Spanish Literature and Medicine
This article explores the relationship between the alcahueta or bawd, the evil eye, and midwifery in the early modern Spanish cultural imaginary.
Emily Kuffner
doaj +1 more source
In recent decades, archaeological research in major Iberian cities has considerably increased our understanding of industrial facilities in the Early Modern Age.
Busto Zapico, Miguel +1 more
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
The author analyzes the main stages of the research process conducted by domestic historians in the sphere of the European rulers’ power sacralization in the Middle Ages and early Modern Age.
E. N. Deniskevich
doaj +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket +14 more
wiley +1 more source
Domesticating Colour in the Early Modern Age: Dyeing Wool in Black in Portugal
Mastering a colour—as such, its ‘domestication’—involves a weft of technological and symbolic relationships encompassed in the human ability to reproduce a visible colour using the techniques of textile dyeing.
Luís Gonçalves Ferreira
doaj +1 more source

