Results 31 to 40 of about 284,976 (311)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Výskum hradu Dobrá Niva v rokoch 2013 a 2014

open access: yesArchaeologia Historica, 2015
Cieľom príspevku je predstaviť a interpretovať nálezovú situáciu na NKP Hrad Dobrá Niva v katastrálnom území obce Podzámčok, okres Zvolen. Archeologický výskum uskutočnený v rokoch 2013 a 2014 priniesol nové informácie o vrcholno- a neskorostredovekom až
Noémi Beljak Pažinová   +2 more
doaj   +1 more source

Bawds, Midwifery, and the Evil Eye in Golden Age Spanish Literature and Medicine

open access: yesHumanities, 2023
This article explores the relationship between the alcahueta or bawd, the evil eye, and midwifery in the early modern Spanish cultural imaginary.
Emily Kuffner
doaj   +1 more source

The modern kilns

open access: yes, 2022
In recent decades, archaeological research in major Iberian cities has considerably increased our understanding of industrial facilities in the Early Modern Age.
Busto Zapico, Miguel   +1 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

ROYAL POWER SACRALIZATION IN THE MIDDLE AGES AND EARLY MODERN AGE AS STUDIED BY DOMESTIC HISTORIANS IN XX – EARLY XXI CENTURY

open access: yesВестник Кемеровского государственного университета, 2018
The author analyzes the main stages of the research process conducted by domestic historians in the sphere of the European  rulers’ power sacralization in the Middle Ages and early Modern Age.
E. N. Deniskevich
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket   +14 more
wiley   +1 more source

Domesticating Colour in the Early Modern Age: Dyeing Wool in Black in Portugal

open access: yesHeritage
Mastering a colour—as such, its ‘domestication’—involves a weft of technological and symbolic relationships encompassed in the human ability to reproduce a visible colour using the techniques of textile dyeing.
Luís Gonçalves Ferreira
doaj   +1 more source

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