Results 31 to 40 of about 261,267 (263)

Domesticating Colour in the Early Modern Age: Dyeing Wool in Black in Portugal

open access: yesHeritage
Mastering a colour—as such, its ‘domestication’—involves a weft of technological and symbolic relationships encompassed in the human ability to reproduce a visible colour using the techniques of textile dyeing.
Luís Gonçalves Ferreira
doaj   +1 more source

The “Protector de Indios” in Early Modern Age America

open access: yesJournal on European History of Law, 2019
After the Discovery of America, the legal Rights of the native Indians were in issue in the Kingdom of Castile. In the universities of Salamanca and Valladolid, as in its most important colleges the obligations of the Spanish Crown with the defendless ...
István Szászdi
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Women’s Account Books in Venice and the Veneto Region. Material and Emotional Aspects

open access: yesCahiers d’Études Italiennes
In recent years, several studies have focused on women’s everyday writings in the early modern period, highlighting, even in the Italian context, the specific circumstances and the skills with which women of the past engaged in writing and accounting in ...
Maria Adank
doaj   +1 more source

Apports de l’archéologie à la connaissance des économies salicoles sur les côtes de la Manche (Protohistoire-époque moderne)

open access: yesArchéopages, 2019
Recent work has shown that salt-making was one of the most important and long-lasting activities carried out in coastal areas on both sides of the Channel since recent prehistory.
Vincent Carpentier, Cyril Marcigny
doaj   +1 more source

On “shapelings” and “childlings”: a linguistics approach to the emergence of new cultural borders between the unborn and the new-born child in EME (1500-1700)

open access: yesJournal of English Studies, 2020
This contribution aims at exploring the emergence of early-age stereotypes in Early Modern England from a Cultural Linguistics approach to Age Studies, using the Historical Thesaurus of the Oxford English Dictionary as a corpus.
Paloma Tejada-Caller
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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