Results 141 to 150 of about 26,666 (254)

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

The History of the Precordial Early Repolarization and Sudden Death Syndrome, Lately Named Brugada Syndrome. [PDF]

J Clin Med
Martini B.
europepmc   +1 more source

Cellular mechanisms of radiation‐induced myocyte dysfunction: effects on calcium handling, ion channel regulation and mitochondrial energetics

The Journal of Physiology, EarlyView.
Abstract figure legend Dose‐dependent effects of radiation on cardiac electrophysiology and arrhythmia susceptibility. At low radiation doses (left), increased reactive oxygen species (ROS) initiate an ROS–Ca2+ positive feedback loop involving calcium/calmodulin‐dependent protein kinase II (CaMKII) activation, enhanced L‐type Ca2+ current (ICaL ...
Hannah M. Zukowski, Colleen E. Clancy
wiley   +1 more source

Prevalence and Event-Free Follow-Up of the Athlete Early Repolarization Pattern in Professional Athletes. [PDF]

JACC Clin Electrophysiol
Hsieh PN, Churchill TW, Petek BJ, Chukwurah MI, Urbut S, Kim JH, Baggish AL, Whalen JM, Chung EH, Guseh JS, Cardiovascular Performance Program Study Group.   +10 more
europepmc   +1 more source

Radiofrequency catheter ablation of the left ventricular epicardium as an electrophysiological substrate in a patient with idiopathic ventricular fibrillation associated with early repolarization. [PDF]

HeartRhythm Case Rep, 2023
Nakajima I, Takano M, Akashi YJ, Harada T.   +3 more
europepmc   +1 more source

Small‐conductance Ca2⁺‐activated K⁺ channels in cardiac excitation–contraction coupling: Bridging mitochondria, sarcolemma and antiarrhythmic therapy

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondrial SK channel enhancement reduces cardiac arrhythmia trigger. Spontaneous sarcoplasmic reticulum (SR) Ca2+ release via hyperactive RyR2s underlies an increased arrhythmia trigger, promoting early and delayed afterdepolarizations during stress. Hyperactive RyR2s causes rise in cytosolic [Ca2+] during diastole. Clearance
Dmitry Terentyev, Alexey V. Glukhov, Vladimir Bogdanov, Aleksei S. Averin, Roland Veress, Bum‐Rak Choi, Shanna Hamilton, Andriy E. Belevych   +7 more
wiley   +1 more source

Sudden Cardiac Arrest Secondary to Early Repolarization Syndrome. [PDF]

JACC Case Rep, 2021
Chilazi M, Gurakar M, Rosen N, Trivedi R, Vakil RM, Sharma G, Chrispin J.   +6 more
europepmc   +1 more source

Early repolarization: An underinvestigated misnoner [PDF]

Clinical Cardiology, 1997
openaire   +2 more sources

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Clinical manifestations and outcomes of idiopathic ventricular fibrillation and early repolarization syndrome in adolescents: A multicenter cohort study. [PDF]

Heart Rhythm O2
Baek SM, Baek JS, Lee J, Yoon JK, Kwon HW, Ryu YH, Jun SY, Kim MJ, Kim AY, Kim CS, Ban JE, Huh J, Bae EJ, Uhm JS, Song MK.   +14 more
europepmc   +1 more source