Results 141 to 150 of about 5,083,312 (279)

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

open access: yesThe FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti   +3 more
wiley   +1 more source

Outcome of patients with idiopathic ventricular fibrillation and correlation with ECG markers of early repolarization. [PDF]

open access: yesClin Res Cardiol, 2023
Rath B   +8 more
europepmc   +1 more source

A novel rare splice variant of the human voltage‐dependent proton channel hHV1

open access: yesThe FEBS Journal, EarlyView.
Alternative splicing of the human HVCN1 gene produces a rare, very‐long proton channel isoform (hHV1‐vl) containing an additional 47 amino acids at its N terminus. This variant was detected in human tissues, including choroid plexus epithelial cells and lymphomas. Compared with the conventional long isoform (hHV1‐l), hHV1‐vl activates more slowly while
Gustavo Chaves   +7 more
wiley   +1 more source

Early repolarization in adolescent athletes: A gender comparison of ECG and echocardiographic characteristics. [PDF]

open access: yesScand J Med Sci Sports, 2022
Vecchiato M   +8 more
europepmc   +1 more source

Brugada Syndrome in the Pediatric Population: Diagnostic Challenges and Clinical Outcome—Results of the German Multicenter Study COGIA

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
The study examines 76 patients of the German multicenter study COGIA with suspected BrS in 12 centers in Germany. Thirty‐nine patients met the current ESC diagnostic criteria, 34 of whom met the Shanghai Score criteria. Four major arrhythmic events (ACA, SCD, appropriate ICD shock) occurred in the cohort (5.3%), all in the group of patients fulfilling ...
Lea Lippert   +35 more
wiley   +1 more source

Electrocardiographic Changes Associated with Early Repolarization Pattern in Healthy Young Males. [PDF]

open access: yesMedicina (Kaunas), 2022
Frigy A   +4 more
europepmc   +1 more source

Arctic lake trout (Salvelinus namaycush) show evidence of seasonal acclimation of cardiac adrenergic sensitivity but not heat tolerance

open access: yesJournal of Fish Biology, EarlyView.
Abstract Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout (Salvelinus namaycush) acclimatized to winter and summer temperatures to determine the extent to ...
Emily P. Williams   +6 more
wiley   +1 more source

The Dual Face of Fusobacterium nucleatum in Cancer: Foe, Friend or Both?

open access: yesJournal of Periodontal Research, EarlyView.
Fusobacterium nucleatum has established interactions with cancers in humans. However, contrary to a traditional view that these interactions are uniformly pro‐tumoural, recent evidence suggests a more nuanced role, where contact‐dependent and contact‐independent mechanisms may support either tumour progression or restriction depending on tumour site ...
Anjali Chander   +3 more
wiley   +1 more source

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