Results 61 to 70 of about 1,658,969 (302)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Campbell Systematic ReviewsThe issue of students dropping out before completing secondary education is a global concern with significant individual and societal consequences. Various terms, such as Early School Leaving (ESL), Early Leaving from Education and Training (ELET), and ...
Marta Pellegrini +5 more
doaj +1 more source
Early Cannabis Use and School to Work Transition of Young Men [PDF]
, 2017 We study the impact of early cannabis use on the school to work transition of young men. Our empirical approach accounts for common unobserved confounders that jointly affect selection into cannabis use and the transition from school to work using a ...
van Ours, Jan C., Williams, Jenny
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The early school leaving: evolution and affected groups
Avances en Supervisión Educativa, 2011 Nowadays one of the most important challenges from a social analysis perspective of education is referred to early school leaving rate in the context of all school academic performance indicators. This indicator has been selected by the European Union to
Miguel Recio Muñoz +1 more
doaj
FormareCareer guidance and the enhancement of transversal skills are essential tools for preventing early school leaving and fostering active student engagement in their educational paths.
Valentina Pagani +4 more
doaj +1 more source
Revue Internationale d’Éducation de Sèvres, 2004 The phenomenon of early school leaving, or terme italien en italiques (dispersal), has become a relatively marginal issue for Italian education in recent years.
Lorenzo Fischer
doaj +1 more source
Early school-leaving: causes - development - prevention - results of research carried out in the States and in Germany [PDF]
, 2011 Schulabbruch oder Dropout spielt in der Diskussion der deutschen Erziehungswissenschaft bisher nur eine marginale Rolle. Die Belege sind jedoch eindeutig, dass ein fehlender Schulabschluss wie auch der häufig damit verknüpfte Schulabsentismus wesentliche
Hillenbrand, Clemens, Ricking, Heinrich
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source