Results 51 to 60 of about 215,330 (256)
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Non-completed Studies: What Factors Affect Academic Success or Failure?
Central European Journal of Educational Research, 2019 The ratio of early school leavers is 12.5 in Hungary, which means 22nd place within the EU28. Early school leaving is an important issue in all European countries, because those who finished their studies after primary education are more likely ...
Edina Kovács
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Campbell Systematic ReviewsThe issue of students dropping out before completing secondary education is a global concern with significant individual and societal consequences. Various terms, such as Early School Leaving (ESL), Early Leaving from Education and Training (ELET), and ...
Marta Pellegrini +5 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The early school leaving: evolution and affected groups
Avances en Supervisión Educativa, 2011 Nowadays one of the most important challenges from a social analysis perspective of education is referred to early school leaving rate in the context of all school academic performance indicators. This indicator has been selected by the European Union to
Miguel Recio Muñoz +1 more
doaj
FormareCareer guidance and the enhancement of transversal skills are essential tools for preventing early school leaving and fostering active student engagement in their educational paths.
Valentina Pagani +4 more
doaj +1 more source
Revue Internationale d’Éducation de Sèvres, 2004 The phenomenon of early school leaving, or terme italien en italiques (dispersal), has become a relatively marginal issue for Italian education in recent years.
Lorenzo Fischer
doaj +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source