Results 61 to 70 of about 13,647,413 (286)

PROTOCOL: Prevention, Intervention, and Compensation Programs to Tackle School Dropout: An Evidence and Gap Map

Campbell Systematic Reviews
The issue of students dropping out before completing secondary education is a global concern with significant individual and societal consequences. Various terms, such as Early School Leaving (ESL), Early Leaving from Education and Training (ELET), and ...
Marta Pellegrini, Carmen Pannone, Daniela Fadda, Laura Francesca Scalas, Giuliano Vivanet, Amanda Neitzel   +5 more
doaj   +1 more source

Dialoguing educational challenges: Understanding early school leaving and underachievement

Heliyon
This study investigates the perspectives of diverse stakeholders within schools and the broader educational landscape to identify gaps between prevention, intervention, and compensation measures, as outlined in the 2014 Eurydice report, and dimensions of
Sarah Gardezi, Joe O'Hara, Gerry McNamara, Aideen Cassidy, Martin Brown, Michael McNamara   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The early school leaving: evolution and affected groups

Avances en Supervisión Educativa, 2011
Nowadays one of the most important challenges from a social analysis perspective of education is referred to early school leaving rate in the context of all school academic performance indicators. This indicator has been selected by the European Union to
Miguel Recio Muñoz, Manuel de la Cruz Hernández   +1 more
doaj  

The Bioecological Model as a Perspective to Interpret Foreign-born Students' Early School Leaving: a Multifactorial Approach

Encyclopaideia, 2019
This article examines the theoretical implications associated with the study of the phenomenon of early school leaving amongst foreign-born students. Its aim to provide an overview of a theoretical framework able to describe and capture the different ...
Caterina Bembich
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Will they stay? Will they go? Individual characteristics predicting early school leaving in Ireland

, 2008
It is estimated that 18% of young people in Ireland leave school before completing the Leaving Certificate (McCoy & Williams, 2006). The aim of this study was to investigate individual characteristics, and attachment style, involved in early school ...
Byrne, Norah
core   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Rethinking PCTO with Student Voice: opportunities, challenges, and perspectives for combating school dropout

Formare
Career guidance and the enhancement of transversal skills are essential tools for preventing early school leaving and fostering active student engagement in their educational paths.
Valentina Pagani, Martina Rossi, Giuliana Viscuso, Guido Benvenuto, Giulia Pastori   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source