Results 81 to 90 of about 2,026,223 (341)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The early school leaving: evolution and affected groups
Avances en Supervisión Educativa, 2011 Nowadays one of the most important challenges from a social analysis perspective of education is referred to early school leaving rate in the context of all school academic performance indicators. This indicator has been selected by the European Union to
Miguel Recio Muñoz +1 more
doaj
FormareCareer guidance and the enhancement of transversal skills are essential tools for preventing early school leaving and fostering active student engagement in their educational paths.
Valentina Pagani +4 more
doaj +1 more source
Revue Internationale d’Éducation de Sèvres, 2004 The phenomenon of early school leaving, or terme italien en italiques (dispersal), has become a relatively marginal issue for Italian education in recent years.
Lorenzo Fischer
doaj +1 more source
Early school-leaving: causes - development - prevention - results of research carried out in the States and in Germany [PDF]
, 2011 Schulabbruch oder Dropout spielt in der Diskussion der deutschen Erziehungswissenschaft bisher nur eine marginale Rolle. Die Belege sind jedoch eindeutig, dass ein fehlender Schulabschluss wie auch der häufig damit verknüpfte Schulabsentismus wesentliche
Hillenbrand, Clemens, Ricking, Heinrich
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Perspectives in Education, 2011 From text: In The Burden of Education Exclusion: ‘Understanding and Challenging Early School Leaving in Africa’ Jacques Zeelen, Dorothy Nampota, Josje van der Linden and Maximiano Ngabirano (eds) have compiled a book that explores a somewhat awkward ...
Paul Wabike
doaj +3 more sources
Early school-leaving in the Netherlands [PDF]
The role of student-, family- and school factors for early school-leaving in lower secondary educationMost studies on early school-leaving address only partial causes of why some students leave school early.
Traag Tanja, Velden Rolf K.W. van der
core +1 more source
Early Cannabis Use and School to Work Transition of Young Men [PDF]
, 2017 We study the impact of early cannabis use on the school to work transition of young men. Our empirical approach accounts for common unobserved confounders that jointly affect selection into cannabis use and the transition from school to work using a ...
van Ours, Jan C., Williams, Jenny
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source