Results 91 to 100 of about 1,814,700 (309)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Jewish Community of Irkutsk in 1917 - the Late 1930s

RUDN Journal of Russian History
The authors examine the history of the early Soviet period (1917 - late 1930s) of the Jewish community of Irkutsk, which by the beginning of the 20th century was the largest Jewish community in Siberia. The fate of the main choral synagogue, three houses
Elena A. Berman, Elena S. Genina
doaj   +1 more source

Privatization and regional distribution of manufacturing in Turkey [PDF]

The state owned enterprises were crucial in the early stage of industrial development in Turkey. They were producer of basic consumption goods and contributed the building the entrepreneurial understanding, and hence the development of the private sector.
Fatma Dogruel, Suut Dogruel
core  

Feedback Loops and Openness: A Snapshot of the Field Baseline Report [PDF]

, 2015
Fund for Shared Insight ("Shared Insight") is a collaborative effort among funders that pools financial and other resources to make grants to improve philanthropy. Shared Insight believes philanthropy can have a greater social and environmental impact if
ORS Impact
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Building Citywide Systems for Quality: A Guide and Case Studies for Afterschool Leaders [PDF]

, 2012
This guide is intended to help cities strengthen and sustain quality afterschool programs by using an emerging practice known as a quality improvement system (QIS). The guide explains how to start building a QIS or how to further develop existing efforts
Alicia Wilson-Ahlstrom, Charles Smith, Elizabeth Devaney, Nicole Yohalem   +3 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

MORALE AND DISCIPLINE OF THE SOVIET POLICE OFFICERS IN THE LATE 1940s – EARLY 1950s (on archival materials of the Sverdlovsk region)

Электронное приложение к Российскому юридическому журналу, 2019
The article is based on unpublished archival materials of the Center for Documentation of Public Organizations of the Sverdlovsk Region. The author examines the internal state of the Soviet police in the post-war period.
Mamyachenkov Vladimir
doaj   +1 more source

The Directions of Educational Activities of Polish Organizations in West Prussia in the Late Nineteenth and Early Twentieth Century

Studia Paedagogica Ignatiana, 2016
The development of the Polish national movement in West Prussia began with the Spring of Nations. In the face of the Germanization policy of the authorities, Prussian Poles began to create their own organizations designed to maintain Polish identity and ...
Paweł Śpica
doaj   +1 more source