Results 141 to 150 of about 1,825,336 (309)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Literature Review: Diverting Mentally Ill Offenders from Jail [PDF]
, 1997 This literature review describes literature available on the topic of diverting mentally ill offenders from jail; outlines major themes found in the literature; analyzed programs described in the literature by type; and highlights recommendations from ...
Crum, Peter, Langworthy, Robert H.
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Government newspaper of the early twentieth century: organization, personnel, promotion of “Russian State” [PDF]
Vestnik of Orenburg State Pedagogical University. Electronic Scientific Journal, 2021 openaire +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Building Advocacy Capacity: Where Grantees Started [PDF]
, 2009 Describes the baseline levels of core advocacy capacities of groups participating in Consumer Voices for Coverage, a twelve-state initiative to build consumer organizations' network and advocacy capacity.
Debra A. Strong +3 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The Elementary and Secondary Education Act, as Amended by the No Child Left Behind Act: A Primer [PDF]
, 2007 [Excerpt] The primary source of federal aid to K-12 education is the Elementary and Secondary Education Act (ESEA), particularly its Title I, Part A program of Education for the Disadvantaged. The ESEA was initially enacted in 1965 (P.L.
Riddle , Wayne C., Skinner, Rebecca R.
core +3 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Stakeholder Input and Meeting Summary Report [PDF]
, 2009 The Piscataqua Region Estuaries Partnership (PREP) is part of the U.S. Environmental Protection Agency’s (EPA) National Estuary Program, which is a joint local/state/federal program established under the Clean Water Act.
D. B. Truslow Associates
core +1 more source