Results 71 to 80 of about 8,176,008 (306)

Boosted dark matter from primordial black holes produced in a first-order phase transition

Journal of High Energy Physics, 2023
During a cosmological first-order phase transition in a dark sector, fermion dark matter particles χ can form macroscopic Fermi balls that collapse to primordial black holes (PBHs) under certain conditions.
Danny Marfatia, Po-Yan Tseng
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Thermalization effects on the dynamics of growing vacuum bubbles

Journal of High Energy Physics
We study the evolution of growing vacuum bubbles. The bubble walls interact with the surrounding fluid and may, consequently, reach a terminal velocity.
Tomasz Krajewski, Marek Lewicki, Martin Vasar, Ville Vaskonen, Hardi Veermäe, Mateusz Zych   +5 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

On the physical basis of cosmic time [PDF]

, 2008
In this manuscript we initiate a systematic examination of the physical basis for the time concept in cosmology. We discuss and defend the idea that the physical basis of the time concept is necessarily related to physical processes which could ...
Zinkernagel, Henrik, Rugh, Svend E.
core  

Synergies between astroparticle, particle and nuclear physics

, 2019
One overarching objective of science is to further our understanding of the universe, from its early stages to its current state and future evolution. This depends on gaining insight on the universe's most macroscopic components, for example galaxies and
Caterina Doglioni, Doglioni, Caterina, Lund University., Doglioni, Caterina,   +3 more
core   +2 more sources

What happens when supercooling is terminated by curvature flipping of the effective potential?

Journal of High Energy Physics
We explore the nature of a certain type of supercooled phase transition, where the supercooling is guaranteed to end due to the curvature of the finite-temperature effective potential at the origin experiencing a sign flip at some temperature.
Tomasz P. Dutka, Tae Hyun Jung, Chang Sub Shin   +2 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Neutrino-antineutrino asymmetry of CνB on the surface of the round Earth

Journal of High Energy Physics
It has been claimed that the coherent scattering of relic neutrinos with the Earth will result in a neutrino-antineutrino asymmetry of O $$ \mathcal{O} $$ (10−4) on the Earth surface, which is five orders of magnitude larger than the naive model ...
Guo-yuan Huang
doaj   +1 more source