Results 191 to 200 of about 985,100 (309)

Piloting a mobile early warning alert and response system for East and Central Darfur, Sudan. [PDF]

Int Health
Shimizu K, Raja MA, Osman MM, Mahmoud EM, Alzain MA, Ayub R, Woung M, Ahmed S, Evers ES, Elnossery S, Ibragem DFO, Mustafa SKA, Aelbrecht L, Khan MF, Ssentamu SK, Khudari H, Haidar H, Sahbani S, Awadallah HMI, Pavlin BI.   +19 more
europepmc   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Spatial early warning signals to assess economic resilience. [PDF]

iScience
Halleck Vega SM, Patuelli R, van Voorn G, Weinans E.   +3 more
europepmc   +1 more source

A wasted early warning [PDF]

Nature Medicine, 2018
openaire   +2 more sources

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Spatiotemporal Early Warning of Human Brucellosis in Hubei Province Using Coupled Ecological-Time Series Models. [PDF]

Zoonoses Public Health
Chen Q, Abudunaibi B, Zhao X, Bahati J, Wang Y, Rui J, Guan X, Chen T.   +7 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Feasibility study of an integrated earthquake and tsunami early warning system. [PDF]

Sci Rep
Rea R, Scala A, Bernardi F, Elia L, Lorito S, Colombelli S, Festa G, Romano F, Amato A, Zollo A.   +9 more
europepmc   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

Early Warning Scores in Emergency Department Patients Aged 80 Years or Older.

JAMA Netw Open
Covino M, Cacciamani Fanelli PM, Bonadia N, Maccauro V, Della Polla DA, De Matteis G, Piccioni A, Gasbarrini A, Sandroni C, Franceschi F.   +9 more
europepmc   +1 more source