Results 61 to 70 of about 6,266,241 (291)

View Score: An early warning score to detect possible complications among COVID-19 patients

Journal of Family Medicine and Primary Care, 2023
Introduction: Understanding pulmonary function at various phases after coronavirus disease 2019 (COVID-19) infection is critical for determining the exact pathophysiological mechanism of COVID-19.
Meenakshi Bhakare, Rajkumar Nikalje, Reshma Patil, Urvi Shukla, Rupesh Bokade, Gajanan Sakhare, Shardul Joshi, Aditi Pais   +7 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

The development, validation and testing of a vital signs monitoring tool for early identification of deterioration in adult surgical patients [PDF]

, 2011
Patients often exhibit premonitory abnormalities in vital signs before an adverse clinical outcome. Patient survival may depend on the decisions of nurses to call for assistance.
Kyriacos, Una
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A comparison between modified early warning score, worthing physiological scoring system, national early warning score, and rapid emergency medicine score in predicting inhospital mortality in multiple trauma patients

Archives of Trauma Research, 2021
Background and Objectives: Physiological scoring systems could potentially aid emergency department (ED) trauma triage, and allowed clinicians to focus on treating the most severe patients first.
Farhad Heydari, Saeed Majidinejad, Ahmad Ahmadi, Mohammad Nasr-Esfahani, Hossein Shayannejad, Neda Al-Sadat Fatemi   +5 more
doaj   +1 more source

SEWS, Early Warning Score.

, 2020
SEWS, Early Warning Score.
Adam Linder (835002), Bertil Christensson (8474139), Per Åkesson (8474142), Lisa Mellhammar (3103740), Jonas Tverring (4522939), John H. Boyd (3171579), Fredrik Kahn (376653)   +6 more
core   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Early warning scores: unravelling detection and escalation

International Journal of Health Care Quality Assurance, 2015
Purpose – The purpose of this paper is to increase understanding of how patient deterioration is detected and how clinical care escalates when early warning score (EWS) systems are used. Design/methodology/approach – The authors critically review a recent National
Smith, Gary B., Prytherch, David, Meredith, Paul, Schmidt, Paul E.   +3 more
openaire   +3 more sources

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source