Results 61 to 70 of about 55,077 (305)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

How comorbidities impact Early Warning Score as a predictor of 7-day mortality [PDF]

, 2020
BACKGROUND: Early Warning Score systems are used to monitor patients at risk of deterioration. How comorbidities impact Early Warning Score's ability to predict short-term mortality in the emergency department is not fully elucidated.
Liesanth, Janet Yde, Dynesen, Jens Jacob, Ahrensberg, Jette, Janet Yde Liesanth, Jette Ahrensberg, Langsted, Sandra Nima Damsholt, Kirkegaard, Hans, Jessen, Marie Kristine, Marie Kristine Jessen, Hans Kirkegaard, Mackenhauer, Julie; id_orcid, Julie Mackenhauer, Sandra Nima Damsholt Langsted, Jens Jacob Dynesen   +13 more
core   +1 more source

A study to introduce National Early Warning Scores (NEWS) in care homes: Influence on decision‐making and referral processes

Nursing Open, 2022
Aim Early warning scores are commonly used in hospital settings, but little is known about their use in care homes. This study aimed to evaluate the impacts of National Early Warning Scores alongside other measures in this setting.
Philip Hodgson, Jane Greaves, Glenda Cook, Angela Fraser, Lesley Bainbridge   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Benefits of Using Early Warning Scores - A Systematic Review

Applied Medical Informatics, 2023
The Early Warning Scores (EWSs) are tools for bedside evaluation based on five physiological parameters: systolic pressure, pulse, respiratory rate, body temperature and AVPU (alert, voice, pain, unresponsive) score.
Ariana-Anamaria CORDOȘ
doaj  

Adjusting Early Warning Score by clinical assessment: a study protocol for a Danish cluster-randomised, multicentre study of an Individual Early Warning Score (I-EWS)

BMJ Open, 2020
Introduction Track and trigger systems (TTSs) based on vital signs are implemented in hospitals worldwide to identify patients with clinical deterioration. TTSs may provide prognostic information but do not actively include clinical assessment, and their
Lars Simon Rasmussen, Kasper Karmark Iversen, Theis Lange, Gitte Bunkenborg, Pernille B Nielsen, Martin Schultz, Caroline Sophie Langkjaer, Anne Marie Kodal, Niels Egholm Pedersen, John Asger Petersen, Michael Dan Arvig, Christian Sahlholt Meyhoff, Morten Bestle, Bibi Hølge-Hazelton, Anne Lippert, Ove Andersen   +15 more
doaj   +1 more source

The utility of the Rapid Emergency Medicine Score (REMS) compared with three other early warning scores in predicting in-hospital mortality among COVID-19 patients in the emergency department: a multicenter validation study

BMC Emergency Medicine, 2023
Background Many early warning scores (EWSs) have been validated to prognosticate adverse outcomes of COVID-19 in the Emergency Department (ED), including the quick Sequential Organ Failure Assessment (qSOFA), the Modified Early Warning Score (MEWS), and ...
Onlak Ruangsomboon, Nutthida Phanprasert, Supawich Jirathanavichai, Chanokporn Puchongmart, Phetsinee Boonmee, Netiporn Thirawattanasoot, Thawonrat Dorongthom, Nattakarn praphruetkit, Apichaya Monsomboon   +8 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Emergency Department-Paediatric Early Warning Score. [PDF]

Emergency Department-Paediatric Early Warning Score.
Navin P. Boeddha (3366875), Elizabeth V. Ledger (18195907), Stefan A. Unger (2851964), Effua Usuf (334925), Natanael Holband (4593013), Godfrey A. Kavishe (18195901), Kristina Keitel (4529020), Rainer Tan (5991500), Henriëtte A. Moll (9258027), Kevin H. van ‘t Kruys (18195904), Joany M. Zachariasse (3712918), Naomi Kemps (18195898), Abdoulie Faal (6757937), Fatou Secka (5327414), Amadu E. Juliana (10169717), Andrew M. Prentice (195160)   +15 more
core   +1 more source