Results 31 to 40 of about 115,166 (264)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The Early Warning System of the City of Medellín and the Aburrá Valley − SIATA, Colombia: a + 20-year prolific journey

Climate Services
There is an urgent need to implement adaptation measures for weather, climate, and compound extreme events. Here, we present a multi-, inter-, and trans-disciplinary case study on the establishment of a local, operational, integrated, and people-centered
Daniel Ruiz-Carrascal, Ana Beatriz Acevedo, Manuel D. Zuluaga, Gloria Ramírez, Daniel Felipe Ruiz, David Santiago Avellaneda-Jiménez, Alejandra Maria Carmona, Catalina Guzmán, Alejandro Marulanda-Tobón, Maria Eugenia Puerta-Yepes, Luz Jeannette Mejía-Chavarriaga   +10 more
doaj   +1 more source

The Research of Coal and Gas Outburst Warning Based on Logistic Regression and Geographic Information System

Shock and Vibration, 2021
Coal and gas outburst is one of the major disasters in the safety production of coal mine. According to the mechanism of coal and gas outburst, based on the comprehensive analysis of various influencing factors of coal and gas outburst, with the ...
Bo You, Bo Li, Shi Liang Shi, He Qing Liu, Yi Lu, He Li   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Activity-based detection of synthetic cannabinoid receptor agonists in plant materials

Harm Reduction Journal
Background Since late 2019, fortification of ‘regular’ cannabis plant material with synthetic cannabinoid receptor agonists (SCRAs) has become a notable phenomenon on the drug market.
Axelle Timmerman, Margot Balcaen, Vera Coopman, Maarten Degreef, Eline Pottie, Christophe P. Stove   +5 more
doaj   +1 more source

Food packing: A case study of dining out in Beijing

Journal of Integrative Agriculture, 2016
Food waste results in nutritional losses, ecological damage, and environmental pollution. This survey is conducted in Beijing and aims to determine whether food waste can be reduced by food packing when leftovers are produced at the dining table and to ...
Yu WANG, Shi-wei XU, Wen YU, Ahmed Abdul-gafar, Xiao-jie LIU, Jun-fei BAI, Dan ZHANG, Li-wei GAO, Xiao-chang CAO, Yao LIU   +9 more
doaj   +1 more source

Early warning technology of regional security situation of gas disasters

Gong-kuang zidonghua, 2020
In order to further improve the prevention and control capabilities of coal mine gas disasters in China and enhance efficiency of supervision, early warning technology of regional security situation of gas disasters was studied.
ZHANG Qinghua, NING Xiaoliang, SONG Zhiqiang, HE Shudong   +3 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source