Results 41 to 50 of about 833,700 (304)

Activity-based detection of synthetic cannabinoid receptor agonists in plant materials

Harm Reduction Journal
Background Since late 2019, fortification of ‘regular’ cannabis plant material with synthetic cannabinoid receptor agonists (SCRAs) has become a notable phenomenon on the drug market.
Axelle Timmerman, Margot Balcaen, Vera Coopman, Maarten Degreef, Eline Pottie, Christophe P. Stove   +5 more
doaj   +1 more source

Exploring Urban Vitality Characteristics and Interactive Mechanisms at the Community Scale through the Lens of Human Behaviour: A Case Study of Chongqing, China [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Exploring urban vitality characteristics and interactive mechanisms are helpful for formulating policy, advancing urban planning and promoting sustainable development.
J. Sheng, J. Sheng, Y. He, T. Lu, T. Lu, F. Wang, F. Wang, Y. Huang, B. Leng, X. Zhang, Y. Chen   +10 more
doaj   +1 more source

Design and Application of Risk Early Warning System for Subway Station Construction Based on Building Information Modeling Real-Time Model

Advances in Civil Engineering, 2021
The problems faced by subway stations in the construction process are more complex than those by overground buildings. Therefore, the construction risk for such structures is highly unpredictable and the risk management is difficult. Building information
Qianlong Tang, Mingfeng Lei, Binbin Zhu, Limin Peng, Weimin Wu, Chenghua Shi   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Discussion on early warning method of coal and gas outburst

Gong-kuang zidonghua, 2018
Definition of early warning of coal and gas outburst was given, and difference between the early warning and forecasting was clearly pointed out. The early warning of coal and gas outburst was classified from angle of space, time and index system, and ...
ZHAO Xusheng, NING Xiaoliang, ZHANG Qinghua, MA Guolong   +3 more
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Research status of early warning technology of coal and gas outburst and its development trend

Gong-kuang zidonghua, 2019
Research achievements of early warning technology of coal and gas outburst were summarized and analyzed in detail from four aspects: early warning theory of coal and gas outburst, acquisition means of early warning information, early warning index and ...
NING Xiaoliang
doaj   +1 more source

Integrated framework for early warning system in UAE [PDF]

, 2016
Purpose - The impacts and costs of natural disasters on people, properties and environment is often severe when they occur on a large scale and with no warning system in place.
Alhmoudi, A, Aziz, ZUH
core   +1 more source