Results 41 to 50 of about 115,166 (264)

Exploring Urban Vitality Characteristics and Interactive Mechanisms at the Community Scale through the Lens of Human Behaviour: A Case Study of Chongqing, China [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Exploring urban vitality characteristics and interactive mechanisms are helpful for formulating policy, advancing urban planning and promoting sustainable development.
J. Sheng, J. Sheng, Y. He, T. Lu, T. Lu, F. Wang, F. Wang, Y. Huang, B. Leng, X. Zhang, Y. Chen   +10 more
doaj   +1 more source

Design and Application of Risk Early Warning System for Subway Station Construction Based on Building Information Modeling Real-Time Model

Advances in Civil Engineering, 2021
The problems faced by subway stations in the construction process are more complex than those by overground buildings. Therefore, the construction risk for such structures is highly unpredictable and the risk management is difficult. Building information
Qianlong Tang, Mingfeng Lei, Binbin Zhu, Limin Peng, Weimin Wu, Chenghua Shi   +5 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Discussion on early warning method of coal and gas outburst

Gong-kuang zidonghua, 2018
Definition of early warning of coal and gas outburst was given, and difference between the early warning and forecasting was clearly pointed out. The early warning of coal and gas outburst was classified from angle of space, time and index system, and ...
ZHAO Xusheng, NING Xiaoliang, ZHANG Qinghua, MA Guolong   +3 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Research status of early warning technology of coal and gas outburst and its development trend

Gong-kuang zidonghua, 2019
Research achievements of early warning technology of coal and gas outburst were summarized and analyzed in detail from four aspects: early warning theory of coal and gas outburst, acquisition means of early warning information, early warning index and ...
NING Xiaoliang
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

High-Precision Imaging and Dense Vehicle Target Detection Method for Airborne Single-Pass Circular Synthetic Aperture Radar

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Circular synthetic aperture radar (CSAR) has advantages of the omnidirectional detection and high-resolution imaging. However, when CSAR detects the dense target in the observation scene, the phenomena such as the layover effect in the CSAR image may ...
Haozong Liu, Hongtu Xie, Ting Gao, Shiliang Yi, Yuanjie Zhang   +4 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source