Physical, Metabolic, and Microbial Rumen Development in Goat Kids: A Review on the Challenges and Strategies of Early Weaning [PDF]
Animals, 2023 The digestive system of newborn ruminant functions is similar to monogastric animals, and therefore milk flows into the abomasum instead of rumen for digestion.
Mahmoud M. Abdelsattar +5 more
doaj +4 more sources
Early weaning causes small intestinal atrophy by inhibiting the activity of intestinal stem cells: involvement of Wnt/β-catenin signaling [PDF]
Stem Cell Research & Therapy, 2023 Background Early weaning and shorter breastfeeding duration are applied by a proportion of young mothers, especially in the social spheres of poverty-stricken areas.
Junquan Tian +7 more
doaj +2 more sources
Early weaning and biological sex shape long-term immune and metabolic responses in pigs [PDF]
Scientific Reports, 2023 During the early pre and postnatal life, host and environmental factors can impart a major influence on immune development, thus shaping lifelong disease resistance. Two major factors known to influence immune function and mortality in animals and people
Mahsa Fardisi +6 more
doaj +2 more sources
Early Weaning Stress Induces Intestinal Microbiota Disturbance, Mucosal Barrier Dysfunction and Inflammation Response Activation in Pigeon Squabs [PDF]
Frontiers in Microbiology, 2022 Early weaning stress has been reported to impair intestinal health in mammals. Like mammals, weaning of the pigeon squab, an altricial bird, is associated with social, environmental and dietary stress.
Qianqian Xu +5 more
doaj +2 more sources
Cortex Phellodendri Extract Supplementation Alleviates Intestinal Oxidative Stress, Inflammation, and Microbiota Dysbiosis in Early Weaning Piglets [PDF]
AnimalsPiglets’ early weaning frequently encounters intestinal dysfunction and diarrhea that results in growth retardation and even mortality. We previously found Cortex Phellodendri extract (CPE) could relieve post-weaning piglets’ diarrhea whereas the ...
Xinran Huang +5 more
doaj +2 more sources
Dietary protein restriction during pregnancy and/or early weaning reduces the number of goblet cells in the small and large intestines of female mice pups [PDF]
Biochemistry and Biophysics Reports, 2023 Background: It remains unclear whether goblet cell numbers in offspring are altered by maternal nutritional status and/or early weaning. Herein, using a murine model, we clarified whether a low-protein (LP) diet during pregnancy and/or early weaning ...
Haruka Adachi +2 more
doaj +2 more sources
Probiotic Combination of Lactiplantibacillus plantarum M1 and Limosilactobacillus reuteri K4 Alleviates Early Weaning-Induced Intestinal Injury in Lambs via Modulation of Oxidative and Inflammatory Pathways [PDF]
AntioxidantsEarly weaning in intensive lamb production improves reproductive efficiency but predisposes lambs to diarrhea, oxidative stress, and intestinal barrier dysfunction, highlighting the need for non-antibiotic strategies to protect gut health.
Qicheng Lu +8 more
doaj +2 more sources
Early Weaning Inhibits Intestinal Stem Cell Expansion to Disrupt the Intestinal Integrity of Duroc Piglets via Regulating the Keap1/Nrf2 Signaling [PDF]
AntioxidantsThere are different stress resistance among different breeds of pigs. Changes in intestinal stem cells (ISCs) are still unclear among various breeds of piglets after early weaning. In the current study, Taoyuan Black and Duroc piglets were slaughtered at
Ying-Chao Qin +7 more
doaj +2 more sources
Impact of Early Weaning on Development of the Swine Gut Microbiome. [PDF]
Microorganisms, 2023 St-Pierre B +2 more
europepmc +2 more sources
Glutamine boosts intestinal stem cell-mediated small intestinal epithelial development during early weaning: Involvement of WNT signaling. [PDF]
Stem Cell Reports, 2023 Tian J +8 more
europepmc +2 more sources