Results 221 to 230 of about 4,835,504 (248)
British Journal of Haematology, EarlyView.Higher chimeric antigen receptor‐T expansion at day 7 is associated with improved progression‐free survival but also increased toxicity in axi‐cel treated patients with R/R large B‐cell lymphoma, independent of other baseline patient and disease characteristics.
Brydon Panozzo +17 more
wiley +1 more source
Brain Pathology, EarlyView.D1R and D2R MSNs show distinct responses to Huntington's pathology. G&T‐sequencing of pre‐symptomatic MSNs reveals global LINE‐1 downregulation. While D1R‐MSNs display early transcriptomic changes (OXPHOS/translation upregulation) and reduced mutant huntingtin aggregation, D2R‐MSNs exhibit higher nuclear mHTT accumulation and greater CAG somatic ...
Guendalina Bergonzoni +22 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu +10 more
wiley +1 more source
Cancer Science, EarlyView.Mice expressing only mutant PTEN Y138L, a protein which shows normal suppression of cellular AKT yet lacks protein phosphatase activity, die in utero, and heterozygous mice display a range of tumors. This indicates both the lipid and protein phosphatase activities of PTEN work together for normal tumor suppression and embryonic development.
Priyanka Tibarewal +16 more
wiley +1 more source
Community Dentistry and Oral Epidemiology, EarlyView.ABSTRACT Objectives This questionnaire‐based study aimed to assess parent‐reported caries (PRC) at ages 2–5 years and identify potential influencing factors using an exploratory, repeated cross‐sectional analysis within an ongoing birth‐cohort study.
Áine M. Lennon +31 more
wiley +1 more source
Peer Pressure: Do the Fitness Benefits of Animal Behavioral Traits Vary With Conspecific Density?
Ethology, EarlyView.We show that the activity of juvenile North American red squirrels influenced their survival in a density‐dependent manner: more active individuals had higher survival under high conspecific density, whereas less active juveniles had higher survival under low densities. Juveniles who were both more active and aggressive were more likely to survive. Our
Deborah Ho +5 more
wiley +1 more source
Fisheries Management and Ecology, EarlyView.ABSTRACT Artisanal gillnet fisheries can concentrate prey and provide incidental food subsidies to marine predators, but their effects on early‐life foraging behavior and demography remain poorly resolved. The Alvarado bottlenose dolphin population that lives off the coast of Veracruz, Mexico, is well known for having chronic, frequent, and recurring ...
Eduardo Morteo +5 more
wiley +1 more source
International Journal of Management Reviews, EarlyView.Abstract The intersection of gender, time and marginalization in organizations is evident in the challenges faced by employed mothers, particularly those who are breastfeeding. These challenges are amplified for Muslim mothers, who must navigate intersecting social identities within these structures shaped by dominant masculine norms.
Feranaaz Farista, Ameeta Jaga
wiley +1 more source