Results 71 to 80 of about 305,009 (232)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Fifteenth century earth science [PDF]

, 1967
The earth science content of two late medieval encyclopedias, the Mirrour of the World and Higden's Polychronicon, both printed by William Caxton in the 1480's, is examined in relation to fifteenth century ideas about the physical nature of the earth and
Stokes, Evelyn
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Interplanetary Mission Performance Assessment of a TANDEM Electric Thruster-Based Spacecraft

Applied Sciences
The aim of this paper is to analyze the transfer performance of a spacecraft equipped with a TANDEM electric propulsion system in a classical interplanetary mission scenario targeting Mars, Venus, or a near-Earth asteroid. The TANDEM concept is a coaxial,
Alessandro A. Quarta
doaj   +1 more source

On the reliability of the so far performed tests for measuring the Lense-Thirring effect with the LAGEOS satellites

, 2005
In this paper we will show in detail that the performed attempts aimed at the detection of the general relativistic Lense-Thirring effect in the gravitational field of the Earth with the existing LAGEOS satellites are often presented in an optimistic and
Allison, Casotto, Cheng, Ciufolini, Ciufolini, Ciufolini, Ciufolini, Ciufolini, Ciufolini, Ciufolini, Ciufolini, Eanes, Everitt, Gruber, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Iorio, Kaula, Lense, Lucchesi, Lucchesi, Lucchesi, Lucchesi, Lucchesi, Lucchesi, Lämmerzahl, Lämmerzahl, Mashhoon, Nordtvedt, Pavlis, Pavlis, Reigber, Reigber, Reigber, Reigber, Ries, Ruggiero, Schiff, Schäfer, Tapley, Tapley, Vespe, Will   +53 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Nature, origin and significance of a clayey cave deposit: Relationship between karst and Oligocene/Miocene tephra (NW Dinarides)

The Depositional Record
A limestone cave filled with montmorillonite clay was found in a hill above the karst plateau on the north‐eastern edge of the Adriatic Sea. The cave fill shows no correlation with sediments found in the surrounding caves or other known caves of the ...
Nadja Zupan Hajna, Pavel Bosák, Andrej Mihevc, Michał Banaś, Jiří Filip, Lukáš Krmíček, Lenka Lisá, Šárka Matoušková, Jan Rohovec, Roman Skála, Jiří Sláma, Martin Šťastný, Jaromír Ulrych   +12 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source