Results 171 to 180 of about 158,108 (314)

Copernicus Data Space Ecosystem establishes public cloud processing for earth observation data. [PDF]

Sci Data
D Kovács D, Musial J, Bojanowski J, Clarijs D, de la Mar J, Zlinszky A.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Probabilistic machine learning for noisy labels in Earth observation. [PDF]

Sci Rep
Kondylatos S, Bountos NI, Prapas I, Zavras A, Camps-Valls G, Papoutsis I.   +5 more
europepmc   +1 more source

Deforestation inhibits malaria transmission in Lao PDR: a spatial epidemiology using Earth observation satellites. [PDF]

Trop Med Health, 2023
Matsumoto-Takahashi ELA, Iwagami M, Oyoshi K, Sasaki Y, Hongvanthong B, Kano S.   +5 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

The CHOVE-CHUVA Earth observation platform to monitor socio-environmental dynamics in Mato Grosso, Brazil. [PDF]

Sci Rep
Arvor D, Denize J, Rouxel L, Dubreuil V, Ribeiro UM, Funatsu BM, Betbeder J, Bégué A, Silgueiro V, da Silva CA, Dias AP, Simões M, Ferraz RPD, Kuchler P, Bellec A.   +14 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Assessing sustained high-heat multi-hazard events through earth observation and impact chain analysis in southeast UK. [PDF]

iScience
Mills E, Smith K, Winson A, Bateson L, Ciurean R.   +4 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Mind the gap: reconciling tropical forest carbon flux estimates from earth observation and national reporting requires transparency. [PDF]

Carbon Balance Manag, 2023
Heinrich V, House J, Gibbs DA, Harris N, Herold M, Grassi G, Cantinho R, Rosan TM, Zimbres B, Shimbo JZ, Melo J, Hales T, Sitch S, Aragão LEOC.   +13 more
europepmc   +1 more source