Results 81 to 90 of about 110,705 (315)

Analysis of Lava from the Cumbre Vieja Volcano Using Remote Sensing Data from DESIS and Sentinel-2

open access: yesRemote Sensing
On 19th September 2021, a protracted eruption of the Cumbre Vieja Volcano on the Canary Island of La Palma commenced and continued for a duration of 12 weeks. Lava flows starting from the rift zone at the mid-western flank of Cumbre Vieja advanced toward
Raquel De Los Reyes   +3 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Assessment of C-Band Polarimetric Radar for the Detection of Diesel Fuel in Newly Formed Sea Ice

open access: yesRemote Sensing
There is a heightened risk of an oil spill occurring in the Arctic, as climate change driven sea ice loss permits an increase in Arctic marine transportation.
Leah Hicks   +6 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Geospatial data mining for digital raster mapping

open access: yesGIScience & Remote Sensing, 2019
We performed an in-depth literature survey to identify the most popular data mining approaches that have been applied for raster mapping of ecological parameters through the use of Geographic Information Systems (GIS) and remotely sensed data.
Bruce K. Wylie   +3 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

GlobalBuildingMap — Unveiling the mystery of global buildings

open access: yesScientific Data
Understanding how buildings are distributed globally is crucial to revealing the human footprint on our home planet. This built environment affects local climate, land surface albedo, resource distribution, and many other key factors that influence well ...
Xiao Xiang Zhu   +6 more
doaj   +1 more source

Monitoring Diesel Spills in Freezing Seawater under Windy Conditions Using C-Band Polarimetric Radar

open access: yesRemote Sensing
The risk of oil spills in the Arctic is growing rapidly as anthropogenic activities increase due to climate-driven sea ice loss. Detecting and monitoring fuel spills in the marine environment is imperative for enacting an efficient response to mitigate ...
Mahdi Zabihi Mayvan   +6 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

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