Results 101 to 110 of about 158,108 (314)
Molecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Earth tides, earthquake occurrence and earth deformation
, 2010 An analysis of Earth deformation, earthquakes and tides has been undertakenusing Earth tide and interferometric SAR data from ESA satellites. The abilityof Earth tides to trigger earthquakes has been investigated by measuring thestatistical relationship ...
Kansowa, Tarek
core
Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Miscellaneous applications of deep learning based multi-sensor Earth observation
Multi-sensor Earth observation offers significant potential across several fields by combining data from diverse sources, providing an understanding of the Earth's dynamics.
Ahmad, Tahir +2 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Active and incremental learning for semantic ALS point cloud segmentation
, 2020 Supervised training of a deep neural network for semantic segmentation of point clouds requires a large amount of labelled data. Nowadays, it is easy to acquire a huge number of points with high density in large-scale areas using current LiDAR and ...
Lin, YAPING (Faculty of Geo-Information Science and Earth Observation (ITC), University of Twente)
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Remote Sensing, 2019 In this study, we evaluated three different downscaling approaches to enhance spatial resolution of thermal imagery over Alpine vegetated areas. Due to the topographical and land-cover complexity and to the sparse distribution of meteorological stations ...
Paulina Bartkowiak +2 more
doaj +1 more source