Results 111 to 120 of about 158,108 (314)
, 2011 The Earth Observation Center (EOC) at the German Aerospace Center (DLR) is the center of competence in Germany, providing expertise in earth observation research and development activities, as well as operational tasks for data reception, processing and ...
Reck, Christoph A. W. +4 more
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Scientific ReportsThere is a consensus on the role of protein conformational changes within the photosynthetic antenna that alter the spectral properties of the embedded pigments during regulated heat dissipation, but despite this, the molecular mechanisms involved are ...
Clara García-Martínez +6 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Extension of earth orbits using low-thrust propulsion
, 2010 The primary motivation for the utilization of space for environmental science, and in-particular Earth Observation, is the unique vantage point which a spacecraft can provide.
Anderson, Pamela, Macdonald, M.
core
Explainable Deep Learning: Paradigms for Earth Observation
, 2020 The volume and variety of valuable Earth Observation (EO) images as well as non-EO related data is rapidly growing. The open free data access becomes widespread and has an enormous scientific and socio-economic relevance.
Datcu, Mihai
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Analysis of Lava from the Cumbre Vieja Volcano Using Remote Sensing Data from DESIS and Sentinel-2
Remote SensingOn 19th September 2021, a protracted eruption of the Cumbre Vieja Volcano on the Canary Island of La Palma commenced and continued for a duration of 12 weeks. Lava flows starting from the rift zone at the mid-western flank of Cumbre Vieja advanced toward
Raquel De Los Reyes +3 more
doaj +1 more source