Results 101 to 110 of about 3,446,655 (295)

Preliminary Results on Hydrogen Concentration Time Series in Spring Gases from the Pamir–Western Himalayan Syntaxis: Variability and Tectonic Instability

Applied Sciences
Identifying reliable geochemical signals that reflect crustal stress evolution remains a major challenge in earthquake monitoring. Spring fluids, due to their deep circulation and rapid response, provide an important window into fault-zone processes ...
Jiao Tian, Jingchao Li, Yuwen Wang, Miao He, Shihan Cui, Bingyu Yao, Zhaojun Zeng, Jinyuan Dong, Changhui Ju, Chang Lu, Xiaocheng Zhou   +10 more
doaj   +1 more source

Temperature corrections to earth pressure cells embedded in backfill

"Determining backfill stress is an important part of evaluating mine safety, whether personnel are working in proximity to backfill or in other areas of the mine where backfill is an integral part of regional support.

core   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Trace element detection in anhydrous minerals by micro-scale quantitative nuclear magnetic resonance spectroscopy

Nature Communications
Nominally anhydrous minerals (NAMs) composing Earth’s and planetary rocks incorporate microscopic amounts of volatiles. However, volatile distribution in NAMs and their effect on physical properties of rocks remain controversial. Thus, constraining trace
Yunhua Fu, Renbiao Tao, Lifei Zhang, Shijie Li, Ya-Nan Yang, Dehan Shen, Zilong Wang, Thomas Meier   +7 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Deviatoric stress-induced metallization, layer reconstruction and collapse of van der Waals bonded zirconium disulfide

Communications Chemistry
In contrast to two-dimensional (2D) monolayer materials, van der Waals layered transition metal dichalcogenides exhibit rich polymorphism, making them promising candidates for novel superconductor, topological insulators and electrochemical catalysts ...
Linfei Yang, Junwei Li, Dongzhou Zhang, Yuegao Liu, Qingyang Hu   +4 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Pore Geometry And Permeability Modeling From Pressure Dependence Of Transport Properties In Sandstone [PDF]

, 1989
In this paper, a model of the pore geometry of sandstones is proposed. Three categories of pores are considered: large spherical pores at 4-grain vertices, tube-like throats at 3-grain edges and narrow sheet-like throats at 2-grain faces. Tube-like and
Bernabe, Yves
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source