Results 91 to 100 of about 3,634,993 (297)

Structure and elasticity of CaC2O5 suggests carbonate contribution to the seismic anomalies of Earth’s mantle

Nature Communications
Knowledge of carbonate compounds under high pressure inside Earth is key to understanding the internal structure of the Earth, the deep carbon cycle and major geological events.
Hanyu Wang, Lei Liu, Zihan Gao, Longxing Yang, Gerile Naren, Shide Mao   +5 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Earth Pressure

AbstractOn the most important wall of our diagnosis, a synthesis of the tension results is compared to a theorical approach. A particular focus is done on the elements located at the foot of the wall and interfering with the tension results.
openaire   +1 more source

How to start an Earth First! chapter

, 1990
Outlines Earth First!, its philosophy and tactics, followed by details on how to establish a local ...
Earth First! (Organization)
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Preliminary Results on Hydrogen Concentration Time Series in Spring Gases from the Pamir–Western Himalayan Syntaxis: Variability and Tectonic Instability

Applied Sciences
Identifying reliable geochemical signals that reflect crustal stress evolution remains a major challenge in earthquake monitoring. Spring fluids, due to their deep circulation and rapid response, provide an important window into fault-zone processes ...
Jiao Tian, Jingchao Li, Yuwen Wang, Miao He, Shihan Cui, Bingyu Yao, Zhaojun Zeng, Jinyuan Dong, Changhui Ju, Chang Lu, Xiaocheng Zhou   +10 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Trace element detection in anhydrous minerals by micro-scale quantitative nuclear magnetic resonance spectroscopy

Nature Communications
Nominally anhydrous minerals (NAMs) composing Earth’s and planetary rocks incorporate microscopic amounts of volatiles. However, volatile distribution in NAMs and their effect on physical properties of rocks remain controversial. Thus, constraining trace
Yunhua Fu, Renbiao Tao, Lifei Zhang, Shijie Li, Ya-Nan Yang, Dehan Shen, Zilong Wang, Thomas Meier   +7 more
doaj   +1 more source