Results 81 to 90 of about 3,446,655 (295)

A Comprehensive Review of Open Caisson Modeling Technology: Current Practices and Future Prospects

open access: yesApplied Sciences
The rapid advancement of modern megapolises has led to a dearth of surface space, and, in response, engineers have begun to trial substitutes below ground level.
Jianxiu Wang   +9 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Active State Earth Pressure based on Dubrova’s Method of Redistribution of Pressure

open access: yesElectronic Journal of Structural Engineering, 2018
Modes and magnitude of wall movement have great influence on the distribution of earth pressure behind retaining wall. For gravity retaining wall exerted by cohesionless soil rotating outward about the base, based on Dubrova’s method of redistribution ...
S.C. Wang, F. Xu, Y. Shao
doaj   +1 more source

Fibre Bragg grating based effective soil pressure sensor for geotechnical applications [PDF]

open access: yes, 2009
An effective-soil-pressure sensor for geotechnical applications based on Fibre Bragg Gratings is presented. The sensor simultaneous measures total soil pressure and pore pressure, allowing the calculation of the effective stress of soil.
Ricardo Correia   +17 more
core   +1 more source

EARTH Integrated Archaeology Rapporten 164

open access: yes, 2022
In november 2020 heeft EARTH Integrated Archaeology B.V een verkennend en karterend booronderzoek (IVO-O) uitgevoerd in een plangebied in Almere Oosterwold aan de toekomstige Daniël Goedkoopstraat.
Rumping, MSc S. (EARTH Integrated Archaeology)   +2 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Decoding multicomponent hydrochemical anomalies: a synergistic detection model for earthquake forecasting [PDF]

open access: yesHydrology and Earth System Sciences
The intersection of the Xiaojiang Fault and the Red River Fault at the southeastern margin of the Tibetan Plateau experiences intense tectonic activity, where repeated earthquakes cause variations in thermal spring hydrochemistry.
W. Shao   +15 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Earth Pressure Calculation Method for Deep Foundation Pit Excavation in Chengdu Pebble Stratum Area

open access: yesChengshi guidao jiaotong yanjiu
Objective The existing theoretical calculation method of earth pressure does not take into account the discrete characteristics of pebble stratum such as large porosity and loose structure, and the calculated results are different from the actual earth ...
LI Shu   +3 more
doaj   +1 more source

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