Results 61 to 70 of about 3,446,655 (295)
EARTH Integrated Archaeology Rapporten 148
In juni 2020 heeft EARTH Integrated Archaeology een archeologisch bureauonderzoek (BO) uitgevoerd binnen een plangebied te Nieuw-Lekkerland, gemeente Molenlanden. Het gehele plangebied is opgedeeld in waardes archeologie 2, 4 en 5.
Vanderhoeven, Drs. T. (EARTH Integrated Archaeology) +1 more
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
To select appropriate support structures in foundation pit engineering of underground tunnels for the Hong Kong International Airport (HKIA), this paper proposed the use of inclined-vertical combined interlocked steel pipe piles, which are beneficial for
ZHOU Yi +3 more
doaj +1 more source
Declaration of the Earth Observation Summit [PDF]
This single page document is a declaration of the participants of the Earth Observation Summit held in Washington DC, adopted on July 31, 2003. An affirmation for the need for timely, quality, long-term, global information as a basis for sound decision ...
[Earth Observation Summit]
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Carbonation of Chrysotile under Subduction Conditions
In order to understand the role of serpentine minerals in the global carbon cycle, high-pressure X-ray diffraction (XRD) experiments were performed on chrysotile (Mg3Si2O5(OH)4) using carbon dioxide (CO2) as a pressure medium.
Mihye Kong, Yongjae Lee
doaj +1 more source
Een archeologisch bureauonderzoek (BO)
In opdracht van RPS- Advies en Ingenieursbureau heeft EARTH Integrated Archaeology in juli 2021 een archeologisch bureauonderzoek uitgevoerd in plangebied Sourethweg, gemeente Heerlen.
Rumping, MSc S (EARTH Integrated Archaeology) +2 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

