Results 61 to 70 of about 3,446,655 (295)

EARTH Integrated Archaeology Rapporten 148

open access: yes, 2021
In juni 2020 heeft EARTH Integrated Archaeology een archeologisch bureauonderzoek (BO) uitgevoerd binnen een plangebied te Nieuw-Lekkerland, gemeente Molenlanden. Het gehele plangebied is opgedeeld in waardes archeologie 2, 4 en 5.
Vanderhoeven, Drs. T. (EARTH Integrated Archaeology)   +1 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Numerical Simulation Analysis on Support Performance of Inclined-Vertical Combined Double-Row Interlocked Steel Pipe Piles

open access: yesZhongwai Gonglu
To select appropriate support structures in foundation pit engineering of underground tunnels for the Hong Kong International Airport (HKIA), this paper proposed the use of inclined-vertical combined interlocked steel pipe piles, which are beneficial for
ZHOU Yi   +3 more
doaj   +1 more source

Declaration of the Earth Observation Summit [PDF]

open access: yes, 2003
This single page document is a declaration of the participants of the Earth Observation Summit held in Washington DC, adopted on July 31, 2003. An affirmation for the need for timely, quality, long-term, global information as a basis for sound decision ...
[Earth Observation Summit]
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Carbonation of Chrysotile under Subduction Conditions

open access: yesEngineering, 2019
In order to understand the role of serpentine minerals in the global carbon cycle, high-pressure X-ray diffraction (XRD) experiments were performed on chrysotile (Mg3Si2O5(OH)4) using carbon dioxide (CO2) as a pressure medium.
Mihye Kong, Yongjae Lee
doaj   +1 more source

Een archeologisch bureauonderzoek (BO)

open access: yes, 2022
In opdracht van RPS- Advies en Ingenieursbureau heeft EARTH Integrated Archaeology in juli 2021 een archeologisch bureauonderzoek uitgevoerd in plangebied Sourethweg, gemeente Heerlen.
Rumping, MSc S (EARTH Integrated Archaeology)   +2 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

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