Results 61 to 70 of about 3,634,993 (297)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Numerical Simulation Analysis on Support Performance of Inclined-Vertical Combined Double-Row Interlocked Steel Pipe Piles

open access: yesZhongwai Gonglu
To select appropriate support structures in foundation pit engineering of underground tunnels for the Hong Kong International Airport (HKIA), this paper proposed the use of inclined-vertical combined interlocked steel pipe piles, which are beneficial for
ZHOU Yi   +3 more
doaj   +1 more source

Toward The Simulation Of Attenuation: Oscillatory Flow In Porous Rock [PDF]

open access: yes, 1998
Fluid flow in porous rock due to an oscillatory pressure gradient is simulated. We observe distributions of density and velocity in the rock which point to viscous dissipation.
Olson, John F.
core  

Passive Earth Pressure in Narrow Cohesive-Frictional Backfills

open access: yes, 2023
A narrow backfill zone is formed when retaining walls are built near existing stabilized structures (e.g., rock faces). In such circumstances, the classical passive earth pressure coefficient is no longer applicable, and a correction factor is required ...
Huang, Hanhui (author)   +9 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Thematische collectie: EARTH Integrated Archaeology

open access: yes, 2015
Overzicht van de in het e-depot gearchiveerde projecten van EARTH Integrated ...
EARTH Integrated Archaeology
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Carbonation of Chrysotile under Subduction Conditions

open access: yesEngineering, 2019
In order to understand the role of serpentine minerals in the global carbon cycle, high-pressure X-ray diffraction (XRD) experiments were performed on chrysotile (Mg3Si2O5(OH)4) using carbon dioxide (CO2) as a pressure medium.
Mihye Kong, Yongjae Lee
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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