Results 41 to 50 of about 3,446,655 (295)
Study on the Earth Pressure during Sinking Stage of Super Large Caisson Foundation
End resistance is a dominant variable in the sinking process of super-sized caisson foundation, which is of great importance to the safe sinking of the caisson foundation.
Jiahang Li, Xuechao Dong, Mingwei Guo
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Experimental Evidence for Partially Dehydrogenated ε-FeOOH
Hydrogen in hydrous minerals becomes highly mobile as it approaches the geotherm of the lower mantle. Its diffusion and transportation behaviors under high pressure are important in order to understand the crystallographic properties of hydrous minerals.
Yukai Zhuang +5 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Alumina nanoparticle-induced decarbonation at subduction-zone conditions
The evolution of calcium carbonate in subduction zones exerts profound effects on Earth’s long-term climate dynamics and planetary habitability. Here, we report the first experimental study to elucidate the influence of aluminum oxide particle size on ...
Jun Hu +9 more
doaj +1 more source
The preparation of dense Si3N4-based ceramics has attracted great attention because of the achievable improvements in their mechanical properties and high-temperature oxidation resistance.
Wei Li +12 more
doaj +1 more source
Thematische collectie: EARTH Integrated Archaeology
Overzicht van de in het e-depot gearchiveerde projecten van EARTH Integrated ...
EARTH Integrated Archaeology
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Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CALCULATION OF SEISMICALLY LOADED EARTH RETAINING STRUCTURES
Eurocode 1998-5 for the design of earth retaining structures in seismic conditions describes calculations using the Mononobe-Okabe method. This simplified quasi-static procedure is to some extent very conservative.
Jan Pruška, Veronika Pavelcová
doaj +1 more source

