Results 31 to 40 of about 97,366 (264)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Experimental Evidence for Partially Dehydrogenated ε-FeOOH

Crystals, 2019
Hydrogen in hydrous minerals becomes highly mobile as it approaches the geotherm of the lower mantle. Its diffusion and transportation behaviors under high pressure are important in order to understand the crystallographic properties of hydrous minerals.
Yukai Zhuang, Zhongxun Cui, Dongzhou Zhang, Jin Liu, Renbiao Tao, Qingyang Hu   +5 more
doaj   +1 more source

CALCULATION OF SEISMICALLY LOADED EARTH RETAINING STRUCTURES

Acta Polytechnica CTU Proceedings, 2022
Eurocode 1998-5 for the design of earth retaining structures in seismic conditions describes calculations using the Mononobe-Okabe method. This simplified quasi-static procedure is to some extent very conservative.
Jan Pruška, Veronika Pavelcová
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Alumina nanoparticle-induced decarbonation at subduction-zone conditions

Communications Chemistry
The evolution of calcium carbonate in subduction zones exerts profound effects on Earth’s long-term climate dynamics and planetary habitability. Here, we report the first experimental study to elucidate the influence of aluminum oxide particle size on ...
Jun Hu, Jin Liu, Yifeng Zhu, Penghui Sun, Ao Deng, Chaojia Lv, Liangxu Xu, Fengxia Sun, Lei Li, Yongjun Tian   +9 more
doaj   +1 more source

High-pressure synthesis, mechanical properties, and oxidation behavior of advanced boron-containing α/β-Si3N4/Si ceramics using polymer-derived amorphous SiBN ceramics

Journal of Advanced Ceramics
The preparation of dense Si3N4-based ceramics has attracted great attention because of the achievable improvements in their mechanical properties and high-temperature oxidation resistance.
Wei Li, Shuailing Ma, Siwen Cui, Jingxue Ding, Marc Widenmeyer, Xiaoqi Zhang, Ying Zhan, Zhaoju Yu, Wenshu Zhang, Pinwen Zhu, Tian Cui, Anke Weidenkaff, Ralf Riedel   +12 more
doaj   +1 more source

Study on Dynamic Response Characteristics of Stepped Reinforced Retaining Wall

Buildings, 2022
In order to further explore the influence of reinforcement materials laying position on the dynamic characteristics of reinforced retaining walls, based on FLAC3D finite difference methods for solving nonlinear problems, established with the same size of
Yalin Zhu, Renyi Chen, Yixian Wang, Juxiang Chen   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source