Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Electrokinetics in Earth Sciences
International Journal of Geophysics, 2013 Laurence Jouniaux, Tsuneo Ishido
doaj +1 more source
Applications of ISES for vegetation and land use [PDF]
Remote sensing relative to applications involving vegetation cover and land use is reviewed to consider the potential benefits to the Earth Observing System (Eos) of a proposed Information Sciences Experiment System (ISES).
Wilson, R. Gale
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The Lyell Collection at the Earth Sciences Department, Natural History Museum, London (UK). [PDF]
Biodivers Data J, 2019 Sendino C.
europepmc +1 more source
Earth science: What triggers reversals of the Earth's magnetic field? [PDF]
, 1984 J. A. Jacobs
openalex +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Analysis of an advisor-advisee relationship: an exploratory study of the area of exact and Earth sciences in Brazil. [PDF]
PLoS One, 2015 Tuesta EF +5 more
europepmc +1 more source
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
Molecular Oncology, EarlyView.PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source
Global Precipitation Measurement (GPM) Mission Products and Services at the NASA Goddard Earth Sciences (GES) Data and Information Services Center (DISC). [PDF]
Bull Am Meteorol Soc, 2017 Liu Z +6 more
europepmc +1 more source