Results 51 to 60 of about 1,474,341 (311)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Approach for characterizing technology- and infrastructure-induced linkages between sustainable development goals

STAR Protocols
Summary: Technology and infrastructure investments targeting a primary sustainable development goal (SDG) can impact other SDGs. Understanding how linkages are shaped by technology characteristics is vital to design efforts that deliberately leverage co ...
Magdalena M. Klemun, Sanna Ojanperä, Amy Schweikert   +2 more
doaj   +1 more source

Resolving spatiotemporal characteristics of the seasonal hypoxia cycle in shallow estuarine environments of the Severn River and South River, MD, Chesapeake Bay, USA

Heliyon, 2016
The nature of emerging patterns concerning water quality stressors and the evolution of hypoxia within sub-estuaries of the Chesapeake Bay has been an important unresolved question among the Chesapeake Bay community.
Andrew C. Muller, Diana L. Muller, Arianna Muller   +2 more
doaj   +1 more source

Opportunities for Characterizing Geological Flows Using Magnetic Resonance Imaging

iScience, 2020
Summary: Geological flows—from mudslides to volcanic eruptions—are often opaque and consist of multiple interacting phases. Scaled laboratory geological experiments using analog materials have often been limited to optical imaging of flow exteriors or ex
Einat Lev, Christopher M. Boyce
doaj   +1 more source

Space life sciences: A status report [PDF]

, 1990
The scientific research and supporting technology development conducted in the Space Life Sciences Program is described. Accomplishments of the past year are highlighted. Plans for future activities are outlined.

core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Protocol to calculate the climate effects of the global aviation industry using the Aviation-FAIR model

STAR Protocols
Summary: The rapid growth of the aviation industry has significantly impacted global climate change. We present a protocol to assess the climate effects of global aviation emissions.
Qiang Cui, Ying Zhou
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protocol for extraction and analysis of microplastics in freshwater, sediment, and fish samples

STAR Protocols
Summary: Microplastic pollution threatens aquatic ecosystems and food webs. Here, we present a protocol for extracting microplastics from freshwater, sediment, and fish digestive system samples.
Tuncay Vural, Soner Çetinkaya, Vedat Yeğen, Selman Şapcıoğlu, Sedat Gündoğdu   +4 more
doaj   +1 more source

Neutrino tomography - Learning about the Earth's interior using the propagation of neutrinos

, 2006
Because the propagation of neutrinos is affected by the presence of Earth matter, it opens new possibilities to probe the Earth's interior. Different approaches range from techniques based upon the interaction of high energy (above TeV) neutrinos with ...
A. B. Borisov, A. B. Borisov, A. De Rujula, A. Nicolaidis, A. Nicolaidis, B. Jacobsson, C. Giunti, C. Kuo, C. Quigg, E. K. Akhmedov, G. Fogli, G. Masters, I. P. Nedyalkov, J. Ahrens, J. Bouchez, J. Burguet-Castell, L. Wolfenstein, M. Apollonio, M. Lindner, M. M. Reynoso, P. Huber, P. Jain, P. Zucchelli, R. J. Geller, S. Geer, S. M. Bilenky, S. P. Mikheev, S. P. Mikheev, S. T. Petcov, T. L. Wilson, T. Ohlsson, T. Ohlsson, T. Ohlsson, W. Winter, Walter Winter, Y. Fukuda, Y. Itow   +36 more
core   +1 more source