Results 111 to 120 of about 250,403 (271)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Shaping Interconnected Geography in Central and Eastern European Academia—Key Research Challenges for the Future

open access: yesGeo: Geography and Environment
Central and Eastern European geography, shaped by its entanglement of natural and social sciences, provides a distinctive lens for rethinking the unity of the discipline.
Mariusz Lamentowicz   +3 more
doaj   +1 more source

Graduate Catalog, 1966-1967 [PDF]

open access: yes, 1966
https://scholar.valpo.edu/gradcatalogs/1003/thumbnail ...
Valparaiso University
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

William John Burchell: The multi-skilled polymath

open access: yesSouth African Journal of Science, 2012
On the bicentenary of William John Burchell's sojourn and journey in southern Africa, we review his contribution to science in the region. In November 1810, Burchell arrived in Cape Town and, in mid-1811, he set off on a 4-year, 7000-km journey of ...
Roger Stewart, Brian Warner
doaj   +4 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Estimation of flow rate calculation errors on the example of five rapid response catchments in the Mecsek Hills

open access: yesHungarian Geographical Bulletin, 2013
Today flash floods are one of the most significant extreme weather-related natural hazards. Due to the global climate change and altered land use, intense runoff and flash floods may exert catastrophic hydrologic impacts on developed areas.
Péter Hegedűs   +4 more
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

MASTERING THE FRENCH LANGUAGEIN AND BY SCHOOL DISCIPLINESLanguage practicesand the report in writing in school subjects in collegein French, history-geography, life and earth sciences and physical education and sportsComparative approach

open access: yes, 2017
Cette recherche a pour objet l'étude de la contribution des disciplines, à l'évolution descollégiens dans leur maîtrise de la langue française. La position de la France dans lesévaluations PISA et les nouvelles préoccupations de l'Union Européenne en matière d'égalitédes chances amènent notre système scolaire à reconsidérer la place du langage dans ...
openaire   +1 more source

Population pressure and global markets drive a decade of forest cover change in Africa\u27s Albertine Rift [PDF]

open access: yes, 2017
Africa\u27s Albertine Rift region faces a juxtaposition of rapid human population growth and protected areas, making it one of the world\u27s most vulnerable biodiversity hotspots.
Chapman, Colin A.   +5 more
core   +1 more source

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