Results 81 to 90 of about 16,799,293 (239)

EROSIVE PROCESSES IN THE RURAL AREA OF THE MUNICIPAL DISTRICT OF BALSAS - MA [PDF]

Sociedade & Natureza, 2005
The Geography represents the beginning of all the other sciences that you/they treat of the organization of the terrestrial space, is the science that studies the Earth in his/her diversity in ways, physical interactions and human interventions.The man ...
Lenir Cardoso Brito, Lílian Daniele Pantoja Gonçalves, Francicléia Vieira Ribeiro, Antonio Cordeiro Feitosa   +3 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Opperman, J.J., Moyle, P.B., Larsen, E.W., Florsheim, J.L. and Manfree, A.D.: Floodplains: Processes and Management for Ecosystem Services

Hungarian Geographical Bulletin, 2018
-
Dénes Lóczy
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Assessment of Water Resources under Climate Change in Western Hindukush Region: A Case Study of the Upper Kabul River Basin

Atmosphere
This study aims to estimate the surface runoff and examine the impact of climate change on water resources in the Upper Kabul River Basin (UKRB). A hydrological model was developed using the Soil and Water Assessment Tool (SWAT) from 2009 to 2019.
Tooryalay Ayoubi, Christian Reinhardt-Imjela, Achim Schulte   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Distribution of landslides reconstructed from inventory data and estimation of landslide susceptibility in Hungary

Hungarian Geographical Bulletin, 2019
The complexity of landslides makes it difficult to predict the spatial distribution of landslide susceptibility and hazard. Although in most European countries the basic preconditions for the occurrence of mass movements (rocks and topography) have been ...
Edina Józsa, Dénes Lóczy, Mauro Soldati, Lucian Daniel Drăguţ, József Szabó   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source