Combining Landscape Genomics and Ecological Modelling to Investigate Local Adaptation of Indigenous Ugandan Cattle to East Coast Fever [PDF]
East Coast fever (ECF) is a fatal sickness affecting cattle populations of eastern, central, and southern Africa. The disease is transmitted by the tick Rhipicephalus appendiculatus, and caused by the protozoan Theileria parva parva, which invades host ...
Elia Vajana +20 more
doaj +2 more sources
An Improved Theileria parva Sporozoite Seroneutralization Assay for the Identification of East Coast Fever Immune Correlates [PDF]
Background: Immune correlates of protection are ideal tools to predict treatment or vaccine efficacy. However, the accuracy of the immune correlate and the capability to robustly predict the outcome of a vaccine candidate are determined by the ...
Hannah Chege +10 more
doaj +2 more sources
Epidemiology of East Coast fever (
In this article, we review the epidemiology of East Coast fever (ECF), a tick-borne infection of cattle, in Kenya. The major factors associated with epidemiology of ECF include the agro-ecological zone (AEZ), livestock production system (LPS) and both ...
Gachohi John +4 more
doaj +2 more sources
The control of East Coast fever of cattle by live parasite vaccination: A science-to-impact narrative [PDF]
There is an increasing interest in determining the impact of vaccine technologies developed using public funding targeted at international development, and understanding the factors and ingredients which contribute to the success and impacts of such ...
B.D. Perry
doaj +2 more sources
Infection and treatment method (ITM) vaccine against East Coast fever: reducing the number of doses per straw for use in smallholder dairy herds by thawing, diluting and refreezing already packaged vaccine [PDF]
Background The Infection and Treatment Method (ITM) of vaccination is the only immunization procedure currently available to protect cattle against East Coast fever (ECF), a tick-transmitted disease responsible for losses of several hundreds of millions ...
Ekta Patel +5 more
doaj +2 more sources
Rhipicephalus appendiculatus ticks transmit Theileria parva from persistently infected cattle in the absence of detectable parasitemia: implications for East Coast fever epidemiology [PDF]
Background East Coast fever (ECF) is a devastating disease of cattle and a significant constraint to improvement of livestock production in sub-Saharan Africa.
Cassandra L. Olds +2 more
doaj +2 more sources
Assessing the potential impact of livestock immunisation and acaricide use on controlling the spread of East Coast fever [PDF]
Immunisation of livestock with high-quality vaccines and the use of acaricides are highly ranked tick control strategies worldwide. However, the effects of coupling livestock immunisation and acaricide control on mitigating the spread of East Coast Fever
Mirirai Chinyoka +4 more
doaj +2 more sources
The apicomplexan hemoparasite, Theileria parva, causes East Coast fever (ECF), a frequently fatal disease of African cattle. Vaccine development has been impeded by incomplete understanding of protective immunity following natural exposure or the ...
Mahmoud M. Elnaggar +3 more
doaj +1 more source
In silico identification of Theileria parva surface proteins
East Coast Fever is a devastating African cattle disease caused by the apicomplexan parasite, Theileria parva. Little is known about the cell surface, and few proteins have been identified.
Nitisha Gurav +3 more
doaj +1 more source
Exploring knowledge and management practices on ticks and tick-borne diseases among agro-pastoral communities in Southern Highlands, Tanzania [PDF]
Aim: The current study was conducted to assess the farmers' knowledge and management practices on ticks and tick-borne diseases (TBDs) through individual interview using a structured questionnaire in Mbarali and Momba districts of Mbeya region ...
Isack Ibrahim Kerario +3 more
doaj +1 more source

