Combining Landscape Genomics and Ecological Modelling to Investigate Local Adaptation of Indigenous Ugandan Cattle to East Coast Fever [PDF]
Frontiers in Genetics, 2018 East Coast fever (ECF) is a fatal sickness affecting cattle populations of eastern, central, and southern Africa. The disease is transmitted by the tick Rhipicephalus appendiculatus, and caused by the protozoan Theileria parva parva, which invades host ...
Elia Vajana +20 more
doaj +3 more sources
Infection and treatment method (ITM) vaccine against East Coast fever: reducing the number of doses per straw for use in smallholder dairy herds by thawing, diluting and refreezing already packaged vaccine [PDF]
BMC Veterinary Research, 2019 Background The Infection and Treatment Method (ITM) of vaccination is the only immunization procedure currently available to protect cattle against East Coast fever (ECF), a tick-transmitted disease responsible for losses of several hundreds of millions ...
Ekta Patel +5 more
doaj +3 more sources
Rhipicephalus appendiculatus ticks transmit Theileria parva from persistently infected cattle in the absence of detectable parasitemia: implications for East Coast fever epidemiology [PDF]
Parasites & Vectors, 2018 Background East Coast fever (ECF) is a devastating disease of cattle and a significant constraint to improvement of livestock production in sub-Saharan Africa.
Cassandra L. Olds +2 more
doaj +3 more sources
Immune parameters to p67C antigen adjuvanted with ISA206VG correlate with protection against East Coast fever [PDF]
Vaccine, 2018 Highlights • Three doses of p67C antigen generated stronger immune responses than two doses.• Antibody titers and CD4+ T-cell proliferation correlated with protection against ECF.• The number of doses could not be reduced from three to two without ...
Anna Lacasta, Elias Awino, Roger Pelle
exaly +3 more sources
The control of East Coast fever of cattle by live parasite vaccination: A science-to-impact narrative [PDF]
One Health, 2016 There is an increasing interest in determining the impact of vaccine technologies developed using public funding targeted at international development, and understanding the factors and ingredients which contribute to the success and impacts of such ...
B.D. Perry
doaj +3 more sources
East Coast Fever Carrier Status and Theileria parva Breakthrough Strains in Recently ITM Vaccinated and Non-Vaccinated Cattle in Iganga District, Eastern Uganda. [PDF]
Pathogens, 2023 East Coast fever (ECF) is a tick-borne disease of cattle that hinders the development of the livestock industry in eastern, central and southern Africa. The ‘Muguga cocktail’ live vaccine, delivered by an infection and treatment method (ITM), remains the
Oligo S +5 more
europepmc +2 more sources
Assessment of the Impact of Early Diagnosis and Early Treatment in the Integrated Control of East Coast Fever (ECF) Involving Acquired Immunity Induced by Natural Infection in Ankole Cattle. [PDF]
Pathogens, 2023 The integrated control of East Coast fever (ECF) by early diagnosis and treatment involving acquired immunity induced by natural infection in Ankole cattle was assessed.
Nanteza A +7 more
europepmc +2 more sources
Molecular characterization and population genetics of Theileria parva in Burundi's unvaccinated cattle: Towards the introduction of East Coast fever vaccine. [PDF]
PLoS One, 2021 Theileria parva (T. parva) is a protozoan parasite that causes East Coast fever (ECF). The disease is endemic in Burundi and is a major constraint to livestock development. In this study, the parasite prevalence in cattle in six regions namely; Northern,
Atuhaire DK +8 more
europepmc +2 more sources
Associations between monthly rainfall and mortality in cattle due to East Coast fever, anaplasmosis and babesiosis. [PDF]
Parasitology, 2020 Weather conditions can impact infectious disease transmission, causing mortalities in humans, wild and domestic animals. Although rainfall in dry tropical regions is highly variable over the year, rainfall is thought to play an important role in the ...
Chepkwony R +4 more
europepmc +2 more sources
Sequence diversity of cytotoxic T cell antigens and satellite marker analysis of Theileria parva informs the immunization against East Coast fever in Rwanda. [PDF]
Parasit Vectors, 2020 East Coast fever (ECF) caused by Theileria parva is endemic in Rwanda. In this study, the antigenic and genetic diversity of T. parva coupled with immunization and field challenge were undertaken to provide evidence for the introduction of ECF ...
Atuhaire DK +7 more
europepmc +2 more sources