Apolipoprotein E drives microglia activation in the development of autoimmune uveitis through up-regulation of peptidyl prolyl isomerase F. [PDF]
Zeng S +10 more
europepmc +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Prostate Cancer Index Density, the Ratio of Percentage of Biopsy-Positive Cores to Prostate Volume, and Predicted Lethal Disease in the EAU Intermediate Prognostic Risk Class: Analysis and Implications in 651 Consecutive Patients Treated with Robot-Assisted Radical Prostatectomy at a Tertiary Referral Centre. [PDF]
Porcaro AB +13 more
europepmc +1 more source
Sleep Problems Alter Proximal Risk of Negative Self-Perceptions on Suicide Risk. [PDF]
ABSTRACT Introduction Perceiving oneself as a burden and self‐hate are core drivers of suicidal thoughts and behaviors. Sleep problems also contribute to elevated risk for suicide. These factors are often studied in isolation and the impact of sleep problems on the risk conferred by negative self‐perceptions to suicide is unclear.
Muehlenkamp JJ +3 more
europepmc +2 more sources
Abstract Introduction Temporary ponds in the Mediterranean climate have a high conservation value, but many have been severely destroyed or degraded. Pond restoration and new pond creation have been engaged widely. Evaluations of the success of such operations are generally carried out over 10–15 years and show divergent results over this timeframe. In
Hugo Fontès +5 more
wiley +1 more source
Altered B cell activation contributes to the immunopathogenesis of childhood arthritis-associated uveitis. [PDF]
Jebson BR +14 more
europepmc +1 more source
Evaluation of Loss of the Y Chromosome in Peripheral Blood as a Biomarker for Prostate Cancer
ABSTRACT Background Prostate cancer (PCa) is the most common malignant tumor in men, but the widely used prostate‐specific antigen (PSA) test has limited diagnostic accuracy. Research proposes that the loss of the Y chromosome (LOY) may affect the occurrence and development of prostate cancer, aiming to assess its potential as a diagnostic biomarker to
Jun Lu +10 more
wiley +1 more source
Comparative analysis of EAU, AUA, and NCCN guidelines for the management of non-muscle invasive bladder cancer. [PDF]
Aydın ME, Aykaç A, Kaya C, Sungur M.
europepmc +1 more source
Effect of Dipyridamole on Experimental Autoimmune Uveitis: Reprogrammed Immune Cell Landscape and Reduced Th17 Pathogenicity. [PDF]
Chen B +9 more
europepmc +1 more source
An intrinsically disordered protein, Q20, forms transmembrane condensates with albumin‐loaded lipid and hybrid giant vesicles. Condensate insertion and membrane remodeling depend on giant vesicle size and membrane properties, inducing local lipid coupling without leakage and revealing a robust membrane‐condensate interplay.
Paula De Dios Andres +5 more
wiley +1 more source

