Results 31 to 40 of about 169,022 (378)

Rapid bedside inactivation of Ebola virus for safe nucleic acid tests [PDF]

, 2016
Rapid bedside inactivation of Ebola virus would be a solution for the safety of medical and technical staff, risk containment, sample transport and high-throughput or rapid diagnostic testing during an outbreak.
Bragstad, Karoline, Dudman, Susanne Gjeruldsen, Fomsgaard, Anders, Karlberg, Helen, Kran, Anne Marte Bakken, Lindegren, Gunnel, Mirazimi, Ali, Rosenstierne, Maiken Wors\uf8e, Salata, Cristiano, Stoltz, Malin Lundahl   +9 more
core   +1 more source

Pre-Ebola virus disease laboratory system and related challenges in Liberia

African Journal of Laboratory Medicine, 2016
Prior to the Ebola virus disease outbreak in Liberia, the laboratory system was duplicativefragmented and minimally coordinated. The National Reference Laboratory was conceptualisedto address the existing challenges by promoting the implementation of ...
Stephen B. Kennedy, John B. Dogba, Christine L. Wasunna, Philip Sahr, Candace B. Eastman, Fatorma K. Bolay, Gloria T. Mason, Mark W.S. Kieh   +7 more
doaj   +1 more source

Continental concerted efforts to control the seventh outbreak of Ebola Virus disease in Uganda: The first 90 days of the response

Journal of Public Health in Africa, 2023
On 20th September 2022, Uganda declared the 7th outbreak of Ebola virus disease (EVD) caused by the Sudan Ebola strain following the confirmation of a case admitted at Mubende Regional Referral Hospital.
Jane R. Aceng, Henry K. Bosa, Neema Kamara, Diana Atwine, Henry Mwebesa, Howard Nyika, Katusiime Maureen, Charles Olaro, Atek Kagirita, Mohammed Larmode, Lul p. Riek, Elvis Temfack, Stephanie Salyer, Dativa Aliddeki, Shingai Machingaidze, Festo Mazuguni, Bruce Kirenga, Winters Muttamba, Misaki Wayengera, Mudashir Bbuye, Arthur Kasambula, Daniel Eurien, Akello Grace, Ingrid Ampaire, Isabirye Herbert, Mathew Tut, Donewell Bangure, Wessam Mankoula, Ibrahima Sonko, Alinon N. Kokou, Simon Magodi, Addis Mhiraf, Daniel Bulwadda, Daniel Kyabayinze, Zainah Kabami, Allan Muruta, Rony Bahatungire, Upentho George, Susan Nabadda, Gloria Birungi, Kabanda Richard, Merawi Aragaw, Ahmed O. Ouma   +42 more
doaj   +1 more source

Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir

Viruses, 2019
Remdesivir (GS-5734) is a 1′-cyano-substituted adenosine nucleotide analogue prodrug that shows broad-spectrum antiviral activity against several RNA viruses. This compound is currently under clinical development for the treatment of Ebola virus disease (
E. Tchesnokov, Joy Y. Feng, D. Porter, M. Götte   +3 more
semanticscholar   +1 more source

Real-time, portable genome sequencing for Ebola surveillance

Nature, 2016
The Ebola virus disease epidemic in West Africa is the largest on record, responsible for over 28,599 cases and more than 11,299 deaths. Genome sequencing in viral outbreaks is desirable to characterize the infectious agent and determine its evolutionary
J. Quick, N. Loman, S. Duraffour, J. Simpson, E. Severi, L. Cowley, J. A. Boré, Raymond Koundouno, G. Dudas, A. Mikhail, N. Ouédraogo, B. Afrough, A. Bah, J. H. Baum, B. Becker-Ziaja, J. Boettcher, Mar Cabeza-Cabrerizo, Alvaro Camino-Sanchez, Lisa L. Carter, J. Doerrbecker, T. Enkirch, Isabel Graciela García Dorival, Nicole Hetzelt, J. Hinzmann, Tobias Holm, L. Kafetzopoulou, Michel Koropogui, Abigail Kosgey, Eeva Kuisma, C. Logue, A. Mazzarelli, S. Meisel, M. Mertens, J. Michel, D. Ngabo, K. Nitzsche, Elisa Pallash, L. Patrono, J. Portmann, Johanna Repits, Natasha Y. Rickett, A. Sachse, Katrin Singethan, I. Vitoriano, Rahel L Yemanaberhan, E. Zekeng, Racine Trina, A. Bello, A. Sall, O. Faye, O. Faye, N. Magassouba, C. V. Williams, Victoria Amburgey, L. Winona, E. Davis, J. Gerlach, F. Washington, V. Monteil, M. Jourdain, M. Bererd, A. Camara, H. Somlaré, Abdoulaye Camara, Marianne Gérard, G. Bado, B. Baillet, D. Delaune, K. Nebie, A. Diarra, Yacouba Savane, R. Pallawo, G. Gutierrez, N. Milhano, Isabelle Roger, Christopher Williams, Facinet Yattara, Kuiama Lewandowski, Jamie Taylor, P. Rachwal, D. Turner, G. Pollakis, J. Hiscox, D. Matthews, M. O’Shea, A. Johnston, Duncan R. Wilson, E. Hutley, E. Smit, A. di Caro, R. Woelfel, K. Stoecker, E. Fleischmann, Martin Gabriel, S. Weller, L. Koivogui, B. Diallo, S. Keita, A. Rambaut, P. Formenty, S. Gunther, M. Carroll   +101 more
semanticscholar   +1 more source

Involvement of Surfactant Protein D in Ebola Virus Infection Enhancement via Glycoprotein Interaction [PDF]

Viruses, MDPI, 2018, 11 (1), pp.15, 2019
Since the largest 2014-2016 Ebola virus disease outbreak in West Africa, understanding of Ebola virus infection has improved, notably the involvement of innate immune mediators. Amongst them, collectins are important players in the antiviral innate immune defense.
arxiv   +1 more source

Mathematical modeling of the West Africa Ebola epidemic

eLife, 2015
As of November 2015, the Ebola virus disease (EVD) epidemic that began in West Africa in late 2013 is waning. The human toll includes more than 28,000 EVD cases and 11,000 deaths in Guinea, Liberia, and Sierra Leone, the most heavily-affected countries ...
Jean-Paul Chretien, Steven Riley, Dylan B George   +2 more
doaj   +1 more source

Public health updates from October 2019 to April 2020

Indian Journal of Community and Family Medicine, 2020
Public health is a very dynamic area, were the policies, guidelines, management is continuously monitored and amended to the current situation. Epidemics and pandemics are now frequent and more widespread due to globalization.
Annu Antony, R Akshaya, Jyolsna Nair
doaj   +1 more source

The Social and Political Dimensions of the Ebola Response: Global Inequality, Climate Change, and Infectious Disease [PDF]

, 2016
The 2014 Ebola crisis has highlighted public-health vulnerabilities in Liberia, Sierra Leone, and Guinea – countries ravaged by extreme poverty, deforestation and mining-related disruption of livelihoods and ecosystems, and bloody civil wars in the ...
A Kay, A Mabin, A Petherick, AM Saéz, AR Poteete, AT Price-Smith, BA Israel, C Bayntun, D Healy, DA Oladele, E Goffman, E Roe, G Bankoff, G Mitman, GB Cockerham, H Frumkin, I Rashid, J Chippaux, J Moran-Ellis, JC Cohen, JC Dumont, JD Mayer, JE Pinzon, K Lee, KC Seto, M Karamouzian, M Nichter, N Brenner, NL Klenk, P Wald, R Bloch, R Bloch, R Keil, R Keil, R Shields, RE Kasperson, S Baize, S Harman, S Lewis, SH Ali, SM Teutsch, T Olaniyan   +41 more
core   +1 more source

The journey of remdesivir: from Ebola to COVID-19

Drugs in Context, 2020
Countries around the world are currently fighting the coronavirus disease 2019 (COVID-19) pandemic, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Joe Pardo, Ashutosh M. Shukla, Gajapathiraju Chamarthi, A. Gupte   +3 more
semanticscholar   +1 more source