Results 41 to 50 of about 88,425 (241)
Science Progress, 2016 This paper is the combination of a review on the problems of data collection and modelling efforts of the recent Ebola epidemics. After a brief review of data availability, the modelling frameworks have been discussed. Both deterministic and stochastic models have been reviewed and supplemented with a short discussion of some problems of parameter ...
Kamalaldin, Kamalaldin +2 more
openaire +2 more sources
FEMS Immunology & Medical Microbiology, 1997 Hantavirus pulmonary syndrome (HPS) and Ebola hemorrhagic fever are acute diseases with high mortality rates in humans caused by negative-stranded RNA viruses for which we have no vaccines. These viruses present two very different profiles when their ecology, history, and status as emerging pathogens are considered. This paper will discuss the dynamics
openaire +2 more sources
Ebola : too far or so close? [PDF]
, 2014 The year 2014 has witnessed the escalation of the largest ever Ebola outbreak which started in Guinea, and later spread to other countries in West Africa.
Torpiano, Paul, Pace, David
core
Ferritin as a Nanoparticle Scaffold for Plant‐Produced Next‐Generation Subunit Vaccines
Biotechnology and Bioengineering, EarlyView.ABSTRACT Protein nanoparticles offer an innovative approach to next‐generation subunit vaccine development by displaying antigenic sequences on the nanoparticle surface. Compared to traditional subunit vaccines, protein nanoparticle vaccines often show improved interaction with the immune system due to their particulate size and repetitive epitope ...
Jordan T. VanderBurgt +3 more
wiley +1 more source
Immunity, 2019 Promising vaccines and results from recent clinical trials of therapeutic antibodies against Ebola virus offer hope for an end to this devastating disease. We asked three investigators in the field to share their views on the remaining challenges and important future research directions as we work toward controlling Ebola virus infection.
openaire +2 more sources
Mechanistic Digital Model for Real‐Time Monitoring and Optimization of Adenovirus Production
Biotechnology and Bioengineering, EarlyView.ABSTRACT Adenoviral vectors are a critical vaccine platform, with billions of vaccine doses administered during the COVID‐19 pandemic. In addition, they are promising therapeutics for cancer treatment. To advance their manufacturing, real‐time monitoring of adenovirus production is essential for process optimization, yield improvement, and product ...
Xingge Xu +4 more
wiley +1 more source
From patterns to predictions: a framework for the spatial epidemiology of wildlife diseases
Ecography, EarlyView.Wildlife diseases pose a significant threat to biodiversity conservation, public health, and livestock. Spatial epidemiology provides a robust framework to understand disease dynamics and guide policy and management. However, the rapid proliferation of spatial methods has largely occurred in isolation across disciplines, leaving the field without a ...
Cesar Herraiz, Pelayo Acevedo
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Vaccination across the life course is a cornerstone of preventive health care for girls and women. Although WHO recommends completion of essential vaccines by adolescence, global coverage remains suboptimal. Vaccine‐preventable diseases—including HPV‐related cancers, vaginal, vulvar, anal, oropharyngeal, influenza, pertussis, hepatitis B ...
Hema Divakar +13 more
wiley +1 more source
OXCT1‐driven succinylation of PSMG3 stabilizes the proteasome to facilitate picornavirus replication
iMetaOmics, EarlyView.Upon entering the pig, foot‐and‐mouth disease virus (FMDV) regulates host glycolysis and the citrate cycle by modulating the expression of metabolic enzymes, resulting in changes in post‐translational modifications (PTMs) including succinylation, lactylation, crotonylation, acetylation, and phosphorylation.
Huisheng Liu +9 more
wiley +1 more source
Analysis of the Ebola with a fractional-order model involving the Caputo-Fabrizio derivative [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2023 This paper uses a fractional-order epidemic model to describe the transmission dynamics of the Ebola virus. The proposed model uses the fractional-order derivative in Caputo-Fabrizio’s sense. It calculates the time-independent solutions of the proposed
Nita H Shah, Kapil Chaudhary
doaj