Results 71 to 80 of about 165,346 (280)
Mathematical modeling of the West Africa Ebola epidemic
eLife, 2015 As of November 2015, the Ebola virus disease (EVD) epidemic that began in West Africa in late 2013 is waning. The human toll includes more than 28,000 EVD cases and 11,000 deaths in Guinea, Liberia, and Sierra Leone, the most heavily-affected countries ...
Jean-Paul Chretien +2 more
doaj +1 more source
Fighting Novel Diseases amidst Humanitarian Crises [PDF]
, 2019 Humanitarian crises are becoming more prevalent and, frequently, more complex, in zones of mis-governance, lack of government presence, and even active conflict, marked by public mistrust and insecurity. The WHO and other health emergency responders lack
Friedman, Eric A. +2 more
core +2 more sources
ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication
Advanced Science, EarlyView.During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou +8 more
wiley +1 more source
Risk Management and Healthcare Policy, 2021 Susannah H Mayhew,1 Patrick Milabyo Kyamusugulwa,2 Kennedy Kihangi Bindu,3 Paul Richards,4 Cyrille Kiyungu,5 Dina Balabanova1 1Department of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK; 2Bukavu Medical ...
Mayhew SH +5 more
doaj
Ebola the Enemy: How the U.S. Media Militarized the 2014 Ebola Epidemic [PDF]
, 2017 The 2014 Ebola outbreak shocked the world. In western Africa, the scale of the tragedy was surprising. But equally surprising was the excessively fearful response of the international public to a disease that most public health experts agreed was ...
Chamness, Sarah
core +2 more sources
Projections of Ebola outbreak size and duration with and without vaccine use in Équateur, Democratic Republic of Congo, as of May 27, 2018. [PDF]
, 2018 As of May 27, 2018, 6 suspected, 13 probable and 35 confirmed cases of Ebola virus disease (EVD) had been reported in Équateur Province, Democratic Republic of Congo. We used reported case counts and time series from prior outbreaks to estimate the total
Ackley, Sarah +17 more
core +2 more sources
Advanced Science, EarlyView.This study identifies Membralin as an ER‐phagy receptor that recruits MAN1B1 and VCP to form a selective ERLAD complex. By sensing dense N‐glycan clusters on viral fusion glycoproteins, this ubiquitin‐independent pathway directs SARS‐CoV‐2 spike, Ebola GP, influenza HA, and HIV‐1 Env to lysosomal degradation, thereby limiting viral infectivity ...
Jing Zhang +5 more
wiley +1 more source
Use of Aptamers as Diagnostics Tools and Antiviral Agents for Human Viruses
Pharmaceuticals, 2016 Appropriate diagnosis is the key factor for treatment of viral diseases. Time is the most important factor in rapidly developing and epidemiologically dangerous diseases, such as influenza, Ebola and SARS.
Víctor M. González +3 more
doaj +1 more source
A Wake-Up Call: Lessons from Ebola for the World's Health Systems [PDF]
, 2015 The report ranks the world's poorest countries on the state of their public health systems, finding that 28 have weaker defenses in place than Sierra Leone where, alongside Liberia and Guinea, the current Ebola crisis has already claimed more than 9,500 ...
Luisa Hanna +2 more
core
Dynamics and optimal control of Ebola transmission
, 2016 A major Ebola outbreak occurs in West Africa since March 2014, being the deadliest epidemic in history. As an infectious disease epidemiology, Ebola is the most lethal and is moving faster than in previous outbreaks.
Rachah, Amira, Torres, Delfim F. M.
core +1 more source