Results 151 to 160 of about 1,763,176 (361)
Background The authors report a 1 month follow up of a neonate described as “miracle baby” because she was born Ebola virus disease-free and survived after her mother was infected with Ebola virus during the third trimester of pregnancy.
N. Kasereka Baraka+2 more
doaj +1 more source
Background Most countries in Subsaharan Africa have well-established National Tuberculosis Control Programs with relatively stable routine performances. However, major epidemiological events may result in significant disruptions. In March 2014, the World
Aboubacar Sidiki Magassouba+10 more
doaj +1 more source
Sequential Monte Carlo Filtering Estimation of Ebola Progression in West Africa [PDF]
We use a multivariate formulation of sequential Monte Carlo filter that utilizes mechanistic models for Ebola virus propagation and available incidence data to simultaneously estimate the disease progression states and the model parameters. This method has the advantage of performing the inference online as the new data becomes available and estimates ...
arxiv
The Antiviral Activity of Polyphenols
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard+5 more
wiley +1 more source
Glycosylation and the global virome
Abstract The sugars that coat the outsides of viruses and host cells are key to successful disease transmission, but they remain understudied compared to other molecular features. Understanding the comparative zoology of glycosylation ‐ and harnessing it for predictive science ‐ could help close the molecular gap in zoonotic risk assessment.
Cassandra L. Pegg+4 more
wiley +1 more source
Modeling the case of early detection of Ebola virus disease [PDF]
The most recent Ebola outbreak in West Africa highlighted critical weaknesses in the medical infrastructure of the affected countries, including effective diagnostics tools, sufficient isolation wards, and enough medical personnel. Here, we develop and analyze a mathematical model to assess the impact of early diagnosis of pre-symptomatic individuals ...
arxiv
Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques
Background Despite repeated outbreaks, in particular the devastating 2014–2016 epidemic, there is no effective treatment validated for patients with Ebola virus disease (EVD).
J. Guedj+10 more
semanticscholar +1 more source
Ebola virus is the causative agent of Ebola virus disease, a severe, often fatal illness in humans. So far, there are no US Food and Drug Administration (FDA)-approved therapeutics directed against Ebola virus.
Anne Sadewasser+9 more
doaj
Ebola Virus Persistence in Semen Ex Vivo
On March 20, 2015, a case of Ebola virus disease was identified in Liberia that most likely was transmitted through sexual contact. We assessed the efficiency of detecting Ebola virus in semen samples by molecular diagnostics and the stability of Ebola ...
Robert J. Fischer+4 more
doaj +1 more source
Accumulation of activated natural killer (NK) cells in tissues during Ebola virus infection contributes to Ebola virus disease (EVD) pathogenesis. Yet, immunization with Ebola virus-like particles (VLPs) comprising glycoprotein and matrix protein VP40 ...
Hung Le+3 more
doaj +1 more source