Results 151 to 160 of about 1,763,176 (361)

One month follow up of a neonate born to a mother who survived Ebola virus disease during pregnancy: a case report in the Democratic Republic of Congo

open access: yesBMC Pediatrics, 2019
Background The authors report a 1 month follow up of a neonate described as “miracle baby” because she was born Ebola virus disease-free and survived after her mother was infected with Ebola virus during the third trimester of pregnancy.
N. Kasereka Baraka   +2 more
doaj   +1 more source

Impact of the Ebola virus disease outbreak (2014–2016) on tuberculosis surveillance activities by Guinea’s National Tuberculosis Control Program: a time series analysis

open access: yesBMC Public Health, 2020
Background Most countries in Subsaharan Africa have well-established National Tuberculosis Control Programs with relatively stable routine performances. However, major epidemiological events may result in significant disruptions. In March 2014, the World
Aboubacar Sidiki Magassouba   +10 more
doaj   +1 more source

Sequential Monte Carlo Filtering Estimation of Ebola Progression in West Africa [PDF]

open access: yesarXiv, 2016
We use a multivariate formulation of sequential Monte Carlo filter that utilizes mechanistic models for Ebola virus propagation and available incidence data to simultaneously estimate the disease progression states and the model parameters. This method has the advantage of performing the inference online as the new data becomes available and estimates ...
arxiv  

The Antiviral Activity of Polyphenols

open access: yesMolecular Nutrition &Food Research, EarlyView.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard   +5 more
wiley   +1 more source

Glycosylation and the global virome

open access: yesMolecular Ecology, Volume 32, Issue 1, Page 37-44, January 2023., 2023
Abstract The sugars that coat the outsides of viruses and host cells are key to successful disease transmission, but they remain understudied compared to other molecular features. Understanding the comparative zoology of glycosylation ‐ and harnessing it for predictive science ‐ could help close the molecular gap in zoonotic risk assessment.
Cassandra L. Pegg   +4 more
wiley   +1 more source

Modeling the case of early detection of Ebola virus disease [PDF]

open access: yesarXiv, 2015
The most recent Ebola outbreak in West Africa highlighted critical weaknesses in the medical infrastructure of the affected countries, including effective diagnostics tools, sufficient isolation wards, and enough medical personnel. Here, we develop and analyze a mathematical model to assess the impact of early diagnosis of pre-symptomatic individuals ...
arxiv  

Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

open access: yesPLoS Medicine, 2018
Background Despite repeated outbreaks, in particular the devastating 2014–2016 epidemic, there is no effective treatment validated for patients with Ebola virus disease (EVD).
J. Guedj   +10 more
semanticscholar   +1 more source

Anti-Niemann Pick C1 Single-Stranded Oligonucleotides with Locked Nucleic Acids Potently Reduce Ebola Virus Infection In Vitro

open access: yesMolecular Therapy: Nucleic Acids, 2019
Ebola virus is the causative agent of Ebola virus disease, a severe, often fatal illness in humans. So far, there are no US Food and Drug Administration (FDA)-approved therapeutics directed against Ebola virus.
Anne Sadewasser   +9 more
doaj  

Ebola Virus Persistence in Semen Ex Vivo

open access: yesEmerging Infectious Diseases, 2016
On March 20, 2015, a case of Ebola virus disease was identified in Liberia that most likely was transmitted through sexual contact. We assessed the efficiency of detecting Ebola virus in semen samples by molecular diagnostics and the stability of Ebola ...
Robert J. Fischer   +4 more
doaj   +1 more source

Ebola virus protein VP40 stimulates IL-12– and IL-18–dependent activation of human natural killer cells

open access: yesJCI Insight, 2022
Accumulation of activated natural killer (NK) cells in tissues during Ebola virus infection contributes to Ebola virus disease (EVD) pathogenesis. Yet, immunization with Ebola virus-like particles (VLPs) comprising glycoprotein and matrix protein VP40 ...
Hung Le   +3 more
doaj   +1 more source

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