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Modeling Ebolavirus Budding with Virus Like Particles
2017About 15 years ago, several groups initially described the release of virus like particles (VLPs) upon expression of Ebola virus VP40 in mammalian cells. Further development of the protocol later allowed for the dissection of the Ebola virus budding mechanism and for the identification of critical VP40 residues involved in this process.
Mathieu Mateo+2 more
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Characterization of Ebolavirus Entry
2019Ebola virus disease is a global concern given its periodic occurrence, high lethality, and rapid spread, coupled with a lack of approved therapeutics and vaccines. New tools are needed to gain fundamental insight into the virus life cycle, particularly entry and fusion of the viral envelope with the host membrane, and to combat the spread of the ...
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Editorial: Laboratory preparedness for Ebolavirus disease
Pathology, 2015Sharon C.-A. Chen+7 more
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