Results 61 to 70 of about 1,782,169 (280)

Clinical Characteristics and Concordance of Anti‐MDA5 Antibodies: A Multicenter Australian Study

Arthritis Care &Research, EarlyView.
Objective In Australia, anti‐MDA5 antibodies are exclusively tested by a line immunoblot assay (LIA). The clinical concordance of an LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies. Methods Electronic records of a multisite cohort (patients
Syed B. Ali, Thomas Khoo, Keeran Shivakumar, Adam Caroll, Lauren Hender, Dimitra Beroukas, Kim Griggs, Celina Jin, Theo De Malmanche, Jessica Day, Gabor Major, Vidya Limaye   +11 more
wiley   +1 more source

Epstein-Barr virus latent proteins regulate expression of the anti-apoptotic cellular bfl-1 gene [PDF]

, 2005
The ubiquitous and oncogenic human herpes-virus Epstem-Barr virus (EB V) establishes a latent infection and promotes the long-term survival of the infected host cell by targeting the molecular machinery that controls cell fate decisions, including ...
Smith, Sinéad M.
core   +2 more sources

Assessing the Efficacy of VLP-Based Vaccine against Epstein-Barr Virus Using a Rabbit Model

Vaccines, 2023
Epstein–Barr virus (EBV) is etiologically associated with a number of malignant and non-malignant conditions. Thus, a prophylactic vaccine against this virus could help to reduce the burden of many EBV-associated diseases. Previously, we reported that an
Narendran Reguraman, Asma Hassani, Pretty S. Philip, Dagmar Pich, Wolfgang Hammerschmidt, Gulfaraz Khan   +5 more
doaj   +1 more source

Defining early events of Epstein–Barr virus (EBV) infection in immortalized nasopharyngeal epithelial cells using cell-free EBV infection [PDF]

, 2019
Epstein-Barr virus (EBV) infection is strongly associated with nasopharyngeal carcinoma, a common cancer in Southeast Asia and certain regions of Africa.
Yip, YL, Guan, X, Tsang, CM, Chan, RCK, Liu, T, Tsao, GSW, Deng, W, Lin, W, Zhou, YL, Pang, PS   +9 more
core   +1 more source

Disabling COMPASS Promoter Licensing Shifts HDAC‐Inhibited Gastric Cancer Toward Sustained Transcriptional Suppression During Recovery

Advanced Science, EarlyView.
Combined inhibition of the WDR5 WIN pocket and HDAC activity converts SAHA‐induced hyperacetylation into a promoter state with reduced WDR5–COMPASS association and H3K4me3. MYC/E2F‐linked nascent transcription and biosynthetic recovery are suppressed, while apoptosis and senescence‐like features increase, resulting in sustained growth inhibition in ...
Jintian Song, Hui Yu, Jianping Jiang, Zhihui Jiang, Zhongshi Hong, Xu Zhang, Luchuan Chen, Shenghong Wei, Yi Wang   +8 more
wiley   +1 more source

Epstein–Barr Virus-Specific Immune Control by Innate Lymphocytes

Frontiers in Immunology, 2017
Epstein–Barr virus (EBV) is a potent B cell transforming pathogen in humans. In most persistently EBV-infected individuals, potent cytotoxic lymphocyte responses prevent EBV-associated pathologies.
Christian Münz
doaj   +1 more source

Integrated Multiomic Analysis Reveals an EBV‐Associated MIF–SPP1+ Macrophage Axis Linking Tumor Stemness and Immune Dysfunction in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study maps how Epstein–Barr virus reshapes the cellular ecosystem of nasopharyngeal carcinoma. It identifies SPP1+ macrophages as partners of stemness‐associated tumor cells and dysfunctional T cells, links tumor‐derived MIF to macrophage recruitment and programming, and shows that macrophage‐derived SPP1 promotes tumorsphere formation and impairs
Guo‐Ying Liu, Shu‐Hui Lv, Shui‐Qing He, Yao‐Fei Jiang, Xing‐Si Peng, Jian‐Cong Sun, Fen He, Hai‐Yan Qin, Nian Lu, Wei‐Xin Bei, Lin‐Yu Zhao, Wan‐Qin Shen, Ze‐Yu Zhao, Lin Wang, Yan‐Qun Xiang, Wang‐Zhong Li   +15 more
wiley   +1 more source

MYRIAD PRESENTATIONS OF A COMMON VIRAL INFECTION

Pakistan Armed Forces Medical Journal, 2011
Epstein-Barr virus (EBV) one of the most common human viruses1. It spreads by intimate contact via passage of saliva, but is not a particularly contagious disease2. In most of the patients Primary EBV infection occurs in childhood as subclinical illness
Raheel Iftikhar, Muhammad Babar Khan, Zuhaib Iqbal   +2 more
doaj   +2 more sources

Benign Gastric Ulcer with Epstein-Barr Virus Infection Mimicking Malignant Gastric Ulcer

The Korean Journal of Gastroenterology, 2019
Epstein-Barr virus (EBV) is the cause of infectious mononucleosis, which is characterized by fever, lymphadenopathy, and sore throat. On the other hand, gastrointestinal symptoms of EBV infection like dyspepsia, abdominal pain are non-specific and rarely
Jin Wuk Gwak, Jiwon Yoo, Seong O Suh, Jaeyeon Kim, In Soo Oh, Ji Yoon Bae   +5 more
doaj   +1 more source

Chronic virus infections supress atopy but not asthma in a set of children from a large Latin American city: a cross-section study. [PDF]

, 2011
BACKGROUND: The prevalence of allergic diseases has increased over recent decades in affluent countries, but remains low in rural populations and some non-affluent countries.
Cruz Álvaro C, Dattoli, VC, Cunha, SS, Rodrigues, LC, Veiga, Rafael V., Veiga Rafael V, Cunha, Sergio S., Neuza M Alcantara-Neves, Cunha, Sergio S, Barreto, Maurício L., Veiga, Rafael V, Barreto, Maurício L, Cruz, Álvaro C., Dattoli, Vitor CC, Dattoli, Vitor C. C., Maurício L Barreto, Cunha Sergio S, Alcantara-Neves Neuza M, Sergio S Cunha, Vitor CC Dattoli, Rafael V Veiga, Alcantara-Neves, Neuza M., Dattoli Vitor CC, Alcantara-Neves, Neuza M, Rodrigues Laura C, Cruz, ÁC, Álvaro C Cruz, Phillip J Cooper, Laura C Rodrigues, Cruz, Álvaro C, Barreto, ML, Cooper, Phillip J, Rodrigues, Laura C., Alcantara-Neves, NM, Rodrigues, Laura C, Veiga, RV, Cooper, PJ, Cooper, Philip, Barreto Maurício L, Cooper Phillip J   +39 more
core   +2 more sources