Results 171 to 180 of about 364,577 (337)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Flywheel Training Periodization in Team Sports

Frontiers in Physiology, 2021
Marco Beato, Marco Beato, Sergio Maroto-Izquierdo, José L. Hernández-Davó, Javier Raya-González   +4 more
doaj   +1 more source

Eccentric Hamstring Strength and Interlimb Asymmetry in Professional Football Players: A NordBord-Based Longitudinal Analysis of Two Professional Teams. [PDF]

Life (Basel)
Altuğ T, Söyler M, Yılmaz C, Eraslan M, Aydın AS, Kadı MN, Akyol P, Küçük H.   +7 more
europepmc   +1 more source

Elliptic flow, eccentricity and eccentricity fluctuations

, 2007
Differential studies of elliptic flow are one of the most powerful tools in studying the initial conditions and dynamical evolution of heavy ion collisions. The comparison of data from Cu+Cu and Au+Au collisions taken with the PHOBOS experiment at RHIC provides new information on the interplay between initial geometry and initial particle density in ...
Loizides, Constantin, Alver, B., Back, B.B., Baker, M.D., Ballintijn, M., Barton, D.S., Betts, R.R., Bindel, R., Busza, W., Chai, Z., Chetluru, V., García, E., Gburek, T., Gulbrandsen, K., Hamblen, J., Harnarine, I., Henderson, C., Hofman, D.J., Hollis, R.S., Holynski, R., Holzman, B., Iordanova, A., Kane, J.L., Kulinich, P., Kuo, C.M., Li, W., Lin, W.T., Manly, S., Mignerey, A.C., Nouicer, R., Olszewski, A., Pak, R., Reed, C., Richardson, E., Roland, C., Roland, G., Sagerer, J., Sedykh, I., Smith, C.E., Stankiewicz, M.A., Steinberg, P., Stephans, G.S.F., Sukhanov, A., Szostak, A., Tonjes, M.B., Trzupek, A., van Nieuwenhuizen, G.J., Vaurynovich, S.S., Verdier, R., Veres, G.I., Walters, P., Wenger, E., Willhelm, D., Wolfs, F.L.H., Wosiek, B., Wozniak, K., Wyngaardt, S., Wyslouch, B.   +57 more
openaire   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

From Physiology to Practice: Validation of Eccentric Velocity Monitoring Using an Optoelectronic System. [PDF]

Sensors (Basel)
Martin-Rivera F, Rodrigo-Mallorca D, Vidal-Vidal J, Franco-Grau LM, Saez-Berlanga A, Chulvi-Medrano I.   +5 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The Effect of Cluster Sets and Accentuated Eccentric Loading on Vertical Jump Performance and Strategy During Lower-Body Complex Training. [PDF]

Eur J Sport Sci
Chae S, Jukic I, Merrigan JJ, Smith JC.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source