Results 151 to 160 of about 119,488 (298)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Time course of eccentric hamstring strength recovery after a competitive match in under-20-year-old football players. [PDF]

J Exerc Sci Fit
Rebolledo-Cobos RC, Páez-Almentero J, Rolong-Donado C, Baroni BM.   +3 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Flywheel Training Periodization in Team Sports

Frontiers in Physiology, 2021
Marco Beato, Marco Beato, Sergio Maroto-Izquierdo, José L. Hernández-Davó, Javier Raya-González   +4 more
doaj   +1 more source

Eccentric Hamstring Force Asymmetry After Anterior Cruciate Ligament Reconstruction: A Cross-Sectional Comparison of Independent 12- and 24-Month Postoperative Cohorts. [PDF]

Diagnostics (Basel)
Kakavas G, Malliaropoulos N, Prill R, Forelli F.   +3 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Biomechanics of Copenhagen Adduction Exercise and Eccentric Hip Adductor Exercises on a Novel Isokinetic Dynamometer With Within-Session Repeatability. [PDF]

Scand J Med Sci Sports
Marušič J, Cvjetičanin O, Supej M, Babič J, Šarabon N.   +4 more
europepmc   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Benefits of Four-Tiered Classification of Exercise-Induced Left Ventricular Hypertrophy in Adolescent Athletes. [PDF]

J Clin Med
Szabo D, Babocsay D, Eklics K, Szokodi I, Toth M, Acs P, Cziraki A, Sarszegi Z.   +7 more
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source