Results 51 to 60 of about 1,115 (179)

Low Flow ECCO2R (CONTRO)

, 2015
Dibattito sull'utilizzo in terapia intensiva della tecnica ECCO2R. Partecipanti: per la posizione a favore il prof.
L. Gattinoni
core   +2 more sources

ECCO2R in 12 COVID-19 ARDS Patients With Extremely Low Compliance and Refractory Hypercapnia

Frontiers in Medicine, 2021
Purpose: A phenotype of COVID-19 ARDS patients with extremely low compliance and refractory hypercapnia was found in our ICU. In the context of limited number of ECMO machines, feasibility of a low-flow extracorporeal carbon dioxide removal (ECCO2R ...
Xin Ding, Huan Chen, Hua Zhao, Hongmin Zhang, Huaiwu He, Wei Cheng, Chunyao Wang, Wei Jiang, Jie Ma, Yan Qin, Zhengyin Liu, Jinglan Wang, Xiaowei Yan, Taisheng Li, Xiang Zhou, Yun Long, Shuyang Zhang   +16 more
doaj   +1 more source

Is there still a place for ECCO₂R? [PDF]

Med Klin Intensivmed Notfmed
Das therapeutische Ziel einer extrakorporalen Kohlenstoffdioxid(CO2)-Elimination (ECCO2R) ist die CO2-Entfernung über eine Gasaustauschmembran aus dem Blut, ohne die Oxygenierung relevant zu beeinflussen.
Staudinger T.
europepmc   +2 more sources

Extracorporeal carbon dioxide removal for treatment of exacerbated chronic obstructive pulmonary disease (ORION): study protocol for a randomised controlled trial

Trials, 2021
Background Hypercapnic exacerbations are severe complications of chronic obstructive pulmonary disease (COPD), characterized by negative impact on prognosis, quality of life and healthcare costs.
Tommaso Tonetti, Lara Pisani, Irene Cavalli, Maria Laura Vega, Elisa Maietti, Claudia Filippini, Stefano Nava, V. Marco Ranieri   +7 more
doaj   +1 more source

A 2-year multicenter, observational, prospective, cohort study on extracorporeal CO2 removal in a large metropolis area

Journal of Intensive Care, 2019
Background Extracorporeal carbon dioxide removal (ECCO2R) is a promising technique for the management of acute respiratory failure, but with a limited level of evidence to support its use outside clinical trials and/or data collection initiatives.
J. L. Augy, N. Aissaoui, C. Richard, E. Maury, M. Fartoukh, A. Mekontso-Dessap, R. Paulet, N. Anguel, C. Blayau, Y. Cohen, J. D. Chiche, S. Gaudry, S. Voicu, A. Demoule, A. Combes, B. Megarbane, E. Charpentier, S. Haghighat, M. Panczer, J. L. Diehl   +19 more
doaj   +1 more source

Decapneization as supportive therapy for the treatment of status asthmaticus: a case report

Journal of Medical Case Reports, 2021
Background Acute severe asthma is a life-threatening medical emergency. Characteristics of asthma include increased airway resistance and dynamic pulmonary hyperinflation that can manifest in dangerous levels of hypercapnia and acidosis, with significant
Rossella Esposito, Irene Esposito, Francesco Imperatore, Giovanni Liguori, Fabrizio Gritti, Chiara Cafora, Paolo Francesco Marsilia, Maria De Cristofaro   +7 more
doaj   +1 more source

The Effect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal Compared With Conventional Lung Protective Ventilation on Cardiac Function

Critical Care Explorations
OBJECTIVES:. Lower tidal volume ventilation (targeting 3 mL/kg predicted body weight, PBW) facilitated by extracorporeal carbon dioxide removal (ECCO2R) has been investigated as a potential therapy for acute hypoxemic respiratory failure (AHRF) in the ...
Peter J. McGuigan, MB, BCh, BAO, MRCA, FFICM, Emma M. Bowcock, MBBS (Hons), FCICM, Nicholas A. Barrett, FCICM, Bronagh Blackwood, PhD, Andrew J. Boyle, PhD, MRCP, Andrew J. Cadamy, MBChB, FRCA, FFICM, Luigi Camporota, MD, PhD, FRCP, FFICM, FERS, John Conlon, BSc, Matthew E. Cove, MB ChB, Michael A Gillies, MD, FRCA, FRCP, FFICM, Clíona McDowell, MSc, CSTAT, James J. McNamee, MB ChB, Cecilia M. O’Kane, PhD, Alex Puxty, MB ChB, FRCA, MRCP, DICM, FFICM, Malcolm Sim, MD, Rebecca Parsons-Simmonds, BSE, MSc, BSc, Tamas Szakmany, PhD, EDIC, DESA, FRCA, FFICM, FCCM, Neil Young, MBChB, MRCP, FRCA, FFICM, Sam Orde, MBBS, PhD, FCICM, Daniel F. McAuley, MD, FMedSci   +19 more
doaj   +1 more source

In vitro characterization of PrismaLung+: a novel ECCO2R device [PDF]

Intensive Care Medicine Experimental, 2020
Abstract Background Invasive mechanical ventilation is lifesaving in the setting of severe acute respiratory failure but can cause ventilation-induced lung injury. Advances in extracorporeal CO2 removal (ECCO2R) technologies may facilitate more protective lung ventilation in acute respiratory distress syndrome, and ...
Ingeborg Hospach, Jacques Goldstein, Kai Harenski, John G. Laffey, Dominique Pouchoulin, Manuela Raible, Stefanie Votteler, Markus Storr   +7 more
openaire   +3 more sources

Hypercapnia Induces Mitochondrial Adaptations and Alters Glutamine Metabolism to Drive a Distinct Metabolic Phenotype in Monocytes

Immunology &Cell Biology, EarlyView.
Elevated CO2 (hypercapnia) is a feature of serious lung diseases, for example COPD and contributes to poor patient prognosis through modulation of immune cell function. Here we employ state‐of‐the art metabolomic and isotope tracing approaches to reveal CO2‐dependent mitochondrial alterations linked to suppressed ATP, proline and glutamate levels in ...
Ben Reddan, David E. Phelan, Xiaofei Yin, Lorraine Brennan, Martina Wallace, Eoin P. Cummins   +5 more
wiley   +1 more source

Feasibility and safety of low-flow extracorporeal CO2 removal managed with a renal replacement platform to enhance lung-protective ventilation of patients with mild-to-moderate ARDS

Critical Care, 2018
Background Extracorporeal carbon-dioxide removal (ECCO2R) might allow ultraprotective mechanical ventilation with lower tidal volume (VT) (
Matthieu Schmidt, Samir Jaber, Elie Zogheib, Thomas Godet, Gilles Capellier, Alain Combes   +5 more
doaj   +1 more source