Results 91 to 100 of about 10,510 (219)
BMC Biology, 2018 Background Drosophila is a powerful model for the study of factors modulating innate immunity. This study examines the effect of water-loss dehydration on innate immune responsiveness in the Drosophila renal system (Malpighian tubules; MTs), and how this
Wenjing Zheng +6 more
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Frontiers in Genetics, 2020 Nuclear factor Y (NF-Y) is a heterotrimeric transcription factor with the ability to bind to a CCAAT box in nearly all eukaryotes. However, the function of NF-Y in the life-history traits of insects is unclear.
Hao-Hao Chen +6 more
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Translational control by Belle regulates E74A-dependent ecdysone-triggered responses.
, 2012 A model of how Belle protein regulates a subset of ecdysone-triggered transcriptional responses. E74A protein has two functions: to induce expression of E74A-dependent target genes and to inhibit its own ecdysone-induced transcription.
Robert J. Ihry (116531) +2 more
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A Drosophila ecdysone-deficient model to assess the endocrine disruptor activity of Bisphenol A
Ecotoxicology and Environmental SafetyBisphenol A (BPA) is a well characterized endocrine disruptor that interferes with the activity of a variety of nuclear receptors. For this reason, BPA has the potential to impact the function of the endocrine system and alter cellular physiology.
Patricia Vega-Cuesta +8 more
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Memorias do Instituto Oswaldo Cruz, 2004 The effects of blood components, nerve-cord severance, and ecdysone therapy on the posterior midgut epithelial cells of 5th-instar Rhodnius prolixus nymphs 10 days after feeding were analyzed by transmission electron microscopy. Cutting the nerve-cord of
JM Albuquerque-Cunha +6 more
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br regulates the expression of the ecdysone biosynthesis gene npc1
, 2010 The growth and metamorphosis of insects are regulated by ecdysteroid hormones produced in the ring gland. Ecdysone biosynthesis-related genes are both highly and specifically expressed in the ring gland.
Liu, Zhonghua +5 more
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G3: Genes, Genomes, Genetics, 2018 Targeting gene function with spatial or temporal specificity is a key goal in molecular genetics. CRISPR-Cas9 has greatly facilitated this strategy, but some standard approaches are problematic.
Nhan Huynh +3 more
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Development of Ecdysone-Regulated Lentiviral Vectors
Molecular Therapy, 2005 We have engineered a lentivirus-based gene transfer system to achieve ecdysone-regulated transgene expression. The method combines the wide tropism of lentiviral vectors and the possibility of gene regulation by a small molecule with an excellent pharmacological profile. Using the hematopoietic tissue as a model, we transduced mouse progenitors with an
GALIMI, Francesco +6 more
openaire +2 more sources
Stimulation of JNK Phosphorylation by the PTTH in Prothoracic Glands of the Silkworm, Bombyx mori
Frontiers in Physiology, 2018 In this study, phosphorylation of c-Jun N-terminal kinase (JNK) by the prothoracicotropic hormone (PTTH) was investigated in prothoracic glands (PGs) of the silkworm, Bombyx mori. Results showed that JNK phosphorylation was stimulated by the PTTH in time-
Shi-Hong Gu +4 more
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The regulation of ecdysone synthesis by insulin and PTTH.
, 2013 Brain lobes and the ring gland are indicated. Ecdysone synthesis is triggered when insulin released from the IPCs and PTTH released from the PG-LPs activate the PI3K and Ras pathways, respectively, in the PG. These two pathways, acting together, activate
Michael Stern (150242) +1 more
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