Results 91 to 100 of about 11,970 (214)

A Drosophila CRISPR/Cas9 Toolkit for Conditionally Manipulating Gene Expression in the Prothoracic Gland as a Test Case for Polytene Tissues

open access: yesG3: Genes, Genomes, Genetics, 2018
Targeting gene function with spatial or temporal specificity is a key goal in molecular genetics. CRISPR-Cas9 has greatly facilitated this strategy, but some standard approaches are problematic.
Nhan Huynh   +3 more
doaj   +1 more source

Ecdysone induces transcription and amplification in Sciara coprophila DNA puff II/9A

open access: yes, 2006
DNA replication is normally tightly regulated to ensure the production of only one copy of the genome per cell cycle. However, DNA puffs of the salivary gland giant polytene chromosomes of Sciara coprophila undergo DNA amplification during the normal ...
Nan Wu   +15 more
core   +1 more source

Stimulation of JNK Phosphorylation by the PTTH in Prothoracic Glands of the Silkworm, Bombyx mori

open access: yesFrontiers in Physiology, 2018
In this study, phosphorylation of c-Jun N-terminal kinase (JNK) by the prothoracicotropic hormone (PTTH) was investigated in prothoracic glands (PGs) of the silkworm, Bombyx mori. Results showed that JNK phosphorylation was stimulated by the PTTH in time-
Shi-Hong Gu   +4 more
doaj   +1 more source

Ecdysone-mediated up-regulation of the effector caspase DRICE is required for hormone-dependent apoptosis in Drosophila cells

open access: yes, 2005
The Drosophila steroid hormone ecdysone mediates cell death during metamorphosis by regulating the transcription of a number of cell death genes. The apical caspase DRONC is known to be transcriptionally regulated by ecdysone during development.
Korten, Z., Cakouros, D., Kumar, S.
core   +1 more source

Development of Ecdysone-Regulated Lentiviral Vectors

open access: yesMolecular Therapy, 2005
We have engineered a lentivirus-based gene transfer system to achieve ecdysone-regulated transgene expression. The method combines the wide tropism of lentiviral vectors and the possibility of gene regulation by a small molecule with an excellent pharmacological profile. Using the hematopoietic tissue as a model, we transduced mouse progenitors with an
GALIMI, Francesco   +6 more
openaire   +2 more sources

An arginine-histone methyltransferase, CARMER, coordinates ecdysone-mediated apoptosis in drosophila cells

open access: yes, 2004
© 2004 The American Society for Biochemistry and Molecular BiologyDevelopmentally programmed cell death is regulated by a balance between pro- and anti-death signaling.
Dimitrios Cakouros   +7 more
core   +1 more source

Abutasterone, an ecdysone from abuta velutina

open access: yes, 1983
The ecdysone abutasterone has been isolated from the Amazonian plant Abuta velutina and its structure elucidated by spectral means ...
Arnaldo I. Da Rocha   +9 more
core   +1 more source

Ecdysone concentration by month for infected and uninfected crabs.

open access: yes, 2018
Monthly boxplots of pooled ecdysone concentrations for uninfected and infected crabs are shown. The p-values listed corresponds to the t-test of ecdysone concentration between infected and uninfected crabs for each month.
Joseph S. Pitula (4884532)   +2 more
core   +1 more source

Har-Relish and Har-CL can respond to ecdysone.

open access: yes, 2013
(A) Har-CL promoter activity in response to ecdysone exposure. (a) Dose-related response to ecdysone administration. To conduct luciferase activity assay, recombinant Har-Relish or Har-Rel-D plasmid was transfected into HzAM1 cells that contained Har-CL ...
Cui Yang (282067)   +5 more
core   +1 more source

Global quantitative proteomics reveals novel factors in the ecdysone signaling pathway in Drosophila melanogaster

open access: yes, 2015
The ecdysone signaling pathway plays a major role in various developmental transitions in insects. Recent advances in the understanding of ecdysone action have relied to a large extent on the application of molecular genetic tools in Drosophila. Here, we
Sap, Karen   +6 more
core   +1 more source

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