Results 81 to 90 of about 23,839 (265)
Juvenile hormone regulates body size and perturbs insulin signaling in Drosophila [PDF]
, 2014 The role of juvenile hormone (JH) in regulating the timing and nature of insect molts is well-established. Increasing evidence suggests that JH is also involved in regulating final insect size.
Gokhale, R. H. +8 more
core +1 more source
microRNA-14 as an efficient suppressor to switch off ecdysone production after ecdysis in insects
RNA Biology, 2019 The precise increase and decrease of hormone ecdysone are critical for accurate development in insects. Most previous works focus on transcriptional activation of ecdysone production; however, little is known about the mechanism of switching off ecdysone
K. He +5 more
semanticscholar +1 more source
TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum
Insect Science, EarlyView.RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li +8 more
wiley +1 more source
Unexpected role of the steroid-deficiency protein ecdysoneless in pre-mRNA splicing. [PDF]
PLoS Genetics, 2014 The steroid hormone ecdysone coordinates insect growth and development, directing the major postembryonic transition of forms, metamorphosis. The steroid-deficient ecdysoneless1 (ecd1) strain of Drosophila melanogaster has long served to assess the ...
Ann-Katrin Claudius +4 more
doaj +1 more source
Mechanisms regulating nutrition-dependent developmental plasticity through organ-specific effects in insects [PDF]
, 2013 Nutrition, via the insulin/insulin-like growth factor (IIS)/Target of Rapamycin (TOR) signaling pathway, can provide a strong molding force for determining animal size and shape.
Koyama, Takashi +2 more
core +2 more sources
General and Comparative Endocrinology, 2019 Ecdysone, diapause hormone and a diapause hormone analog are all capable of breaking pupal diapause and prompting initiation of adult development in the cotton earworm, Helicoverpa zea.
Julie A. Reynolds +2 more
semanticscholar +1 more source
Disease Models & Mechanisms, 2020 Aldosterone is produced by the mammalian adrenal cortex to modulate blood pressure and fluid balance; however, excessive, prolonged aldosterone promotes fibrosis and kidney failure.
Wenjing Zheng, Karen Ocorr, Marc Tatar
doaj +1 more source
Inducible, reversible, and stable RNA interference in mammalian cells [PDF]
, 2004 RNA interference is a powerful genetic approach for efficiently silencing target genes. The existing method of gene suppression by the constitutive expression of short hairpin RNAs (shRNAs) allows analysis of the consequences of stably silencing genes ...
Gupta, S. +4 more
core +1 more source
Dpp regulates autophagy-dependent midgut removal and signals to block ecdysone production
Cell Death and Differentiation, 2018 Animal development and homeostasis require the programmed removal of cells. Autophagy-dependent cell deletion is a unique form of cell death often involved in bulk degradation of tissues.
Donna Denton +4 more
semanticscholar +1 more source
Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System
Advanced Science, Volume 13, Issue 23, 23 April 2026.This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi +13 more
wiley +1 more source