Results 1 to 10 of about 1,000 (118)

UVB Radiation Delays Tribolium castaneum Metamorphosis by Influencing Ecdysteroid Metabolism. [PDF]

open access: yesPLoS ONE, 2016
Ultraviolet B (UVB) radiation is an important environmental factor. It is generally known that UVB exhibits high genotoxicity due to causing DNA damage, potentially leading to skin carcinogenesis and aging in mammals.
Wen Sang   +7 more
doaj   +1 more source

Targeting the Nrf2-dependent mechanism of b-Ecdysterone in attenuating the motor dysfunction in the MPTP/Pro-induced Parkinson’s disease mice model

open access: yesFolia Neuropathologica, 2023
Oxidative stress is a pivotal stimulating factor in neurocyte apoptosis and has been involved in the pathogenesis of Parkinson’s disease (PD). In this study, we have demonstrated that the improvement in the motor disorder of 1-methyl-4-phenyl-1,2,3,6 ...
Hua Rong   +8 more
doaj   +1 more source

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

open access: yesVIEW, Volume 7, Issue 3, June 2026.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li   +5 more
wiley   +1 more source

β-Ecdysterone and Sarsasapogenin, first isolated from Polygonatum kingianum, reveal its therapeutic potential in MAFLD via 16S rRNA sequencing and metabolomics

open access: yesJournal of Agriculture and Food Research
Metabolic dysfunction-associated fatty liver disease (MAFLD) is linked to metabolic disorders. Polygonatum kingianum (PK), as a medicinal and edible homologous plant, shows therapeutic potential.
Yue Zhou   +10 more
doaj   +1 more source

Transcriptome Analysis to Identify the Putative Biosynthesis and Transport Genes Associated with the Medicinal Components of Achyranthes bidentata Bl.

open access: yesFrontiers in Plant Science, 2016
Achyranthes bidentata is a popular perennial medicine herb used for thousands of years in China to treat various diseases. Although this herb has multiple pharmaceutical purposes in China, no transcriptomic information has been reported for this species.
Jinting Li   +9 more
doaj   +1 more source

Flower Extracts from Ornamental Plants as Sources of Sunscreen Ingredients: Determination by In Vitro Methods of Photoprotective Efficacy, Antigenotoxicity and Safety

open access: yesMolecules, 2022
Plants are sources of sunscreen ingredients that prevent cellular mutations involved in skin cancer and aging. This study investigated the sunscreen properties of the extracts from some ornamental plants growing in Colombia.
Jorge Luis Fuentes   +6 more
doaj   +1 more source

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

open access: yesDrug Testing and Analysis, Volume 18, Issue 4, Page 458-482, April 2026.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

The Effects and Mechanisms of Pomegranate on Regulating Lipid Metabolism

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
This study established a high‐fat diet‐induced hyperlipidemia rat model to investigate the lipid‐lowering effects of pomegranate. Pomegranate intervention significantly reduced serum total cholesterol (TC), triglyceride (TG), and low‐density lipoprotein cholesterol (LDL‐C) levels, while alleviating hepatic steatosis by decreasing liver weight and fat ...
Hao Wang   +9 more
wiley   +1 more source

Mitochondrial proteomic analysis of ecdysterone protection against oxidative damage in human lens epithelial cells

open access: yesInternational Journal of Ophthalmology, 2014
AIM:To investigate the protective effects of the natural medicinal monomer ecdysterone (ECR) with estrogenic activity against oxidative damage in human lens epithelial cells B3 (HLE-B3) caused by hydrogen peroxide 21(H2O2) and to pursue the possible ...
Chun-Yan Feng   +7 more
doaj   +1 more source

Effects and Mechanisms of Dietary Natural Products on Ischemic Stroke: An Updated Review

open access: yesFood Science &Nutrition, Volume 13, Issue 12, December 2025.
This review mainly summarizes the effects and mechanisms of dietary natural products on ischemic stroke, and highlights future research directions. Overall, this review provides a useful reference for the application of dietary natural products in the prevention and management of ischemic stroke.
Kai‐Yi Zhong   +5 more
wiley   +1 more source

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