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The Sublethal Effects of β-Ecdysterone, a Highly Active Compound from Achyranthes bidentata Blume, on Grape Phylloxera, Daktulosphaira vitifoliae Fitch. [PDF]

open access: yesPLoS ONE, 2016
Grape phylloxera, Daktulosphaira vitifoliae (Fitch) (Hemiptera, Phylloxeridae), is a very destructive insect pest of grapevines. Intercropping of Achyranthes bidentata Blume (f. Amaranthaceae) and Vitis spp. grapevines can be useful to control this pest.
Yongqiang Liu   +6 more
doaj   +3 more sources

β-Ecdysterone Enhanced Bone Regeneration Through the BMP-2/SMAD/RUNX2/Osterix Signaling Pathway [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2022
Bone defects are a global public health problem. However, the available methods for inducing bone regeneration are limited. The application of traditional Chinese herbs for bone regeneration has gained popularity in recent years. β-ecdysterone is a plant
Cai-Ping Yan   +15 more
doaj   +2 more sources

Regulation of osteoblast autophagy based on PI3K/AKT/mTOR signaling pathway study on the effect of β-ecdysterone on fracture healing [PDF]

open access: yesJournal of Orthopaedic Surgery and Research, 2021
Objectives To investigate the effects of β-ecdysterone on fracture healing and the underlying mechanism. Methods MTT assay was used to detect the cell viability. AO/PI and flow cytometry assays were used to determine the apoptotic rate.
Yanghua Tang   +6 more
doaj   +2 more sources

20-Hydroxyecdysone, from Plant Extracts to Clinical Use: Therapeutic Potential for the Treatment of Neuromuscular, Cardio-Metabolic and Respiratory Diseases

open access: yesBiomedicines, 2021
There is growing interest in the pharmaceutical and medical applications of 20-hydroxyecdysone (20E), a polyhydroxylated steroid which naturally occurs in low but very significant amounts in invertebrates, where it has hormonal roles, and in certain ...
Laurence Dinan   +3 more
doaj   +1 more source

Effects of Allium macrostemon Bunge Extract on Adipose Tissue Inflammation and Hepatic Endoplasmic Reticulum Stress in High-Fat Diet-Fed and Bisphenol A-Treated C57BL/6N Mice

open access: yesFoods, 2023
The simultaneous exposure to a high-fat (HF) diet and to bisphenol A (BPA) from delivered foods and food-delivery containers is on the rise in humans, according to the increased frequency of food delivery during the COVID-19 pandemic.
Juhae Kim   +4 more
doaj   +1 more source

Phytoconstituents assessment and development of standardization protocol for ‘Nayopayam Kwatha’, a polyherbal Ayurvedic formulation

open access: yesJournal of Ayurveda and Integrative Medicine, 2021
Background: Nayopayam kwatha (NK) is a well-known polyherbal formulation widely used to cure respiratory ailments, heart problems, and postnatal difficulties.
S. Neethu   +4 more
doaj   +1 more source

Unraveling the potential mechanisms of the anti-osteoporotic effects of the Achyranthes bidentata–Dipsacus asper herb pair: a network pharmacology and experimental study

open access: yesFrontiers in Pharmacology, 2023
Background: Osteoporosis is a prevalent bone metabolism disease characterized by a reduction in bone density, leading to several complications that significantly affect patients’ quality of life. The Achyranthes bidentata–Dipsacus asper (AB–DA) herb pair
Tao Li   +5 more
doaj   +1 more source

Isolation and Purification of Three Ecdysteroids from the Stems of Diploclisia glaucescens by High-Speed Countercurrent Chromatography and Their Anti-Inflammatory Activities In Vitro

open access: yesMolecules, 2017
High-speed counter-current chromatography was used to separate and purify ecdysteroids for the first time from the stems of Diploclisia glaucescens using a two-phase solvent system composed of ethyl acetate–n-butanol–ethanol–water (3:0.2:0.8:3, v/v ...
Lei Fang   +4 more
doaj   +1 more source

Mitochondrial proteomic analysis of ecdysterone protection against oxidative damage in human lens epithelial cells

open access: yesInternational Journal of Ophthalmology, 2014
AIM:To investigate the protective effects of the natural medicinal monomer ecdysterone (ECR) with estrogenic activity against oxidative damage in human lens epithelial cells B3 (HLE-B3) caused by hydrogen peroxide 21(H2O2) and to pursue the possible ...
Chun-Yan Feng   +7 more
doaj   +1 more source

β-Ecdysterone and Sarsasapogenin, first isolated from Polygonatum kingianum, reveal its therapeutic potential in MAFLD via 16S rRNA sequencing and metabolomics

open access: yesJournal of Agriculture and Food Research
Metabolic dysfunction-associated fatty liver disease (MAFLD) is linked to metabolic disorders. Polygonatum kingianum (PK), as a medicinal and edible homologous plant, shows therapeutic potential.
Yue Zhou   +10 more
doaj   +1 more source

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