Results 11 to 20 of about 2,322,244 (160)

β-Ecdysterone Enhanced Bone Regeneration Through the BMP-2/SMAD/RUNX2/Osterix Signaling Pathway [PDF]

Frontiers in Cell and Developmental Biology, 2022
Bone defects are a global public health problem. However, the available methods for inducing bone regeneration are limited. The application of traditional Chinese herbs for bone regeneration has gained popularity in recent years. β-ecdysterone is a plant
Chong Yin, Li Yu-Ling
exaly   +5 more sources

The Sublethal Effects of β-Ecdysterone, a Highly Active Compound from Achyranthes bidentata Blume, on Grape Phylloxera, Daktulosphaira vitifoliae Fitch. [PDF]

PLoS ONE, 2016
Grape phylloxera, Daktulosphaira vitifoliae (Fitch) (Hemiptera, Phylloxeridae), is a very destructive insect pest of grapevines. Intercropping of Achyranthes bidentata Blume (f. Amaranthaceae) and Vitis spp. grapevines can be useful to control this pest.
Yongqiang Liu, Fuqian Yang, Hongtie Pu, Junping Su, Zongjiang Liu, Khalid Hussain Dhiloo, Zhongyue Wang   +6 more
doaj   +4 more sources

Regulation of osteoblast autophagy based on PI3K/AKT/mTOR signaling pathway study on the effect of β-ecdysterone on fracture healing [PDF]

Journal of Orthopaedic Surgery and Research, 2021
Objectives To investigate the effects of β-ecdysterone on fracture healing and the underlying mechanism. Methods MTT assay was used to detect the cell viability. AO/PI and flow cytometry assays were used to determine the apoptotic rate.
Yanghua Tang, Yafeng Mo, Dawei Xin, Zhenfei Xiong, Linru Zeng, Gan Luo, Yanguang Cao   +6 more
doaj   +3 more sources

Characterization and bioactivity of β- ecdysterone from cell cultures of Trianthema decandra L.

Indian Journal of Natural Products and Resources, 2023
617-623In the present study, cell cultures from the nodal explants of Trianthema decandra L. were established on Murashige and Skoog’s (MS) medium supplemented with different concentrations (0.5, 1, 1.5, and 2 mg/L) of indole 3-acetic acid (IAA), 2,4 ...
Pancholi, Boskey
core   +2 more sources

β-Ecdysterone and Sarsasapogenin, first isolated from Polygonatum kingianum, reveal its therapeutic potential in MAFLD via 16S rRNA sequencing and metabolomics

Journal of Agriculture and Food Research
Metabolic dysfunction-associated fatty liver disease (MAFLD) is linked to metabolic disorders. Polygonatum kingianum (PK), as a medicinal and edible homologous plant, shows therapeutic potential.
Yue Zhou, Jie Li, Li Li, Na Shen, Xin-Yi Li, Ni-Man Bao, Xing-Xin Yang, Bin Qiu, Zhen Chen, Wen Gu, Jie Yu   +10 more
doaj   +2 more sources

Quinoa as phytopharmaceutical? Urinary elimination of ecdysterone after consumption of quinoa alone and in combination with spinach [PDF]

Archiv der Pharmazie, Volume 357, Issue 6, June 2024.
The phytosteroid ecdysterone and its metabolites were detected in reasonable amounts in humans after ingestion of quinoa. Future potential of therapeutical applications should be investigated. Abstract The phytosteroid ecdysterone is classified as an anabolic agent and has been included on the monitoring list of the World Anti‐Doping Agency since 2020.
Eduard Isenmann, Tasha Yuliandra, Konstantina Touvleliou, Matthias Broekmann, Xavier de la Torre, Francesco Botrè, Patrick Diel, Maria Kristina Parr   +7 more
wiley   +4 more sources

Ecdysterone Alleviates Atherosclerosis by Inhibiting NCF2 and Inhibiting Ferroptosis Mediated by the PI3K/Akt/Nrf2 Pathway. [PDF]

J Cell Mol Med
ABSTRACT Ecdysterone (Ecd), an active ingredient in trianthema, has a strong anti‐inflammatory effect. This study aimed to explore the potential mechanism by which Ecd improves atherosclerosis (AS). Here, we systematically investigated the mechanism of Ecd in human umbilical vein endothelial cells (HUVECs) treated with oxidised low‐density lipoprotein (
Wang Z, Wu F, Yan J, Liang L, Chang F, Dong M, Diao J, Wu H.   +7 more
europepmc   +2 more sources

Immunomodulatory Mechanisms of Rehmanniae Radix Praeparata-Achyranthes Root-Chinese Angelica Root Combination in Nontraumatic Osteonecrosis of the Femoral Head: A Comprehensive Network Pharmacology and Molecular Docking Study Focusing on Immunological Pathways. [PDF]

Mediators Inflamm
Objective Nontraumatic osteonecrosis of the femoral head (NONFH) is a devastating condition characterised by immune dysregulation and sterile inflammation, which are increasingly acknowledged as central pathogenic mechanisms. This study aims to identify the core herbal combination for NONFH and systematically explore its immunomodulatory effects and ...
Li X, Ng L, Liu C, Qin L, Xiao P, Liu C, Liu Y, Zhang Q, Huang W, Zhou Y.   +9 more
europepmc   +2 more sources

Effect of β‑ecdysterone on glucocorticoid‑induced apoptosis and autophagy in osteoblasts. [PDF]

Mol Med Rep, 2018
The aim of the present study was to investigate the effect of glucocorticoids in osteoblasts and to examine the role of β-ecdysterone in the pathogenesis of glucocorticoid-induced osteoporosis.
Tang YH, Yue ZS, Li GS, Zeng LR, Xin DW, Hu ZQ, Xu CD.   +6 more
europepmc   +2 more sources

β‑Ecdysterone promotes autophagy and inhibits apoptosis in osteoporotic rats. [PDF]

Mol Med Rep, 2018
Osteoporosis is an aging process of skeletal tissues with characteristics of reductions in bone mass and microarchitectural deterioration of bone tissue.
Tang YH, Yue ZS, Xin DW, Zeng LR, Xiong ZF, Hu ZQ, Xu CD.   +6 more
europepmc   +2 more sources